Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449539 | 0.85 | HDAC3 (0.44) | LMNAEDNRAEDNRBKMT2APOLB | |
| SCHEMBL10355854 | 0.82 | EDNRA (0.50) | LMNAEDNRAEDNRBKMT2ACES2 | |
| SCHEMBL11527593 | 0.82 | EDNRA (0.50) | LMNAEDNRAEDNRBKMT2ACES2 | |
| SCHEMBL9449550 | 0.82 | ESR1 (0.40) | LMNASMN1; SMN2KMT2APOLBMEN1 | |
| SCHEMBL8797526 | 0.81 | TSHR (0.42) | LMNAKMT2AMEN1 | |
| SCHEMBL8184983 | 0.81 | TP53 (0.52) | LMNASMN1; SMN2KMT2AHDAC4MEN1 | |
| SCHEMBL1149629 | 0.78 | CHRNB2 (0.40) | LMNASMN1; SMN2KMT2ACES2CES1 | |
| SCHEMBL8188873 | 0.77 | ALDH1A1 (0.45) | LMNAKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL8191725 | 0.77 | KMT2A (0.49) | LMNASMN1; SMN2KMT2AGAAPOLB | |
| SCHEMBL8797377 | 0.77 | TBXA2R (0.44) | KMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975841-B2 | Large molecule and polymer flame retardants | MEGAMATTER, INC. (US) | 2018-05-22 | — | — | US | disclosed |