Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MDH1 | P40925 | 1/20 | 0.43 |
| ▸ | MDH2 | P40926 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622322 | 0.86 | RARA (0.53) | TP53MAPK1TDP1MAPT | |
| SCHEMBL17364032 | 0.84 | MEN1 (0.53) | EPHX2HSP90AA1NPC1TP53MAPK1 | |
| SCHEMBL9622187 | 0.81 | RARA (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5888301 | 0.78 | RARB (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL566894 | 0.78 | CA12 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9622121 | 0.77 | ALDH1A1 (0.53) | CA1CA2NPC1TP53MAPK1 | |
| SCHEMBL8766438 | 0.75 | RARB (0.62) | HIF1AMDH1MDH2EP300EPAS1 | |
| SCHEMBL566278 | 0.74 | RARA (0.62) | EPHX2HIF1AMDH1MDH2EP300 | |
| SCHEMBL566878 | 0.74 | CNR2 (0.53) | EPHX2HIF1AMDH1MDH2EP300 | |
| SCHEMBL9622617 | 0.74 | CA1 (0.56) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093516-A | AROMATIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND FOR COSMETIC COMPOSITIONS | L'OREAL (FR) | 1992-03-03 | — | — | US | disclosed |
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | disclosed |