Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | RARA | P10276 | 6/20 | 0.53 |
| ▸ | RARB | P10826 | 6/20 | 0.53 |
| ▸ | RARG | P13631 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PGR | P06401 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | GOT1 | P17174 | 1/20 | 0.53 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622135 | 0.92 | RARB (0.61) | ALDH1A1RARARARBRARGKMT2A | |
| SCHEMBL6878528 | 0.87 | KMT2A (0.51) | ALDH1A1RARARARBRARGKMT2A | |
| SCHEMBL9622322 | 0.82 | RARA (0.53) | ALDH1A1RARARARBRARGKMT2A | |
| SCHEMBL7904172 | 0.82 | KMT2A (0.48) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL9622143 | 0.81 | RARB (0.48) | ALDH1A1RARARARBRARGKMT2A | |
| SCHEMBL9622379 | 0.80 | RARB (0.50) | ALDH1A1RARARARBRARGKMT2A | |
| SCHEMBL6364425 | 0.78 | RARA (0.71) | ALDH1A1RARARARBRARGKMT2A | |
| SCHEMBL9622361 | 0.78 | RARB (0.55) | ALDH1A1RARARARBRARGKMT2A | |
| SCHEMBL9300831 | 0.77 | RARB (0.69) | ALDH1A1RARARARBRARGKMT2A | |
| SCHEMBL9622186 | 0.77 | CA12 (0.46) | TDP1NPC1MAPK1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093516-A | AROMATIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND FOR COSMETIC COMPOSITIONS | L'OREAL (FR) | 1992-03-03 | — | — | US | disclosed |
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | disclosed |