Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365256 | 0.82 | TSHR (0.52) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9621815 | 0.81 | TSHR (0.45) | ALDH1A1CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL9622292 | 0.81 | ALDH1A1 (0.50) | ALDH1A1NAPRTUSP2TBXAS1HTT | |
| SCHEMBL29817984 | 0.79 | RECQL (0.50) | ALDH1A1NAPRTUSP2TBXAS1HTT | |
| SCHEMBL1161996 | 0.79 | RECQL (0.50) | ALDH1A1NAPRTUSP2TBXAS1HTT | |
| SCHEMBL11875125 | 0.79 | ALDH1A1 (0.49) | ALDH1A1NAPRTUSP2TBXAS1HTT | |
| Hydrochloric Acid SCHEMBL17906582 | 0.78 | RECQL (0.49) | ALDH1A1NAPRTUSP2TBXAS1CYP1A2 | |
| SCHEMBL21387052 | 0.76 | HSPA5 (0.54) | CYP11B1CYP11B2NAPRTTBXAS1HTT | |
| Imidazole SCHEMBL9730632 | 0.76 | TSHR (0.38) | ALDH1A1CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL7439635 | 0.76 | ALDH1A1 (0.58) | ALDH1A1USP2HTTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126357-A | ANTI-INFLAMMATORY PICOLYSELENOBENZAMIDES AND SALTS THEREOF | A. NATTERMANN & CIE. GMBH (DE) | 1992-06-30 | — | — | US | disclosed |