Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365256 | 0.87 | TSHR (0.52) | TSHRCYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL17737239 | 0.82 | TSHR (0.67) | TSHRMAPK1CYP2C9CYP19A1KDM6B | |
| SCHEMBL9622294 | 0.81 | ALDH1A1 (0.47) | CYP11B1CYP11B2CYP2C19CYP1A2CYP2C9 | |
| Imidazole SCHEMBL9730632 | 0.80 | TSHR (0.38) | TSHRCYP11B1CYP11B2CYP2D6CYP2C19 | |
| SCHEMBL9368471 | 0.77 | TSHR (0.47) | TSHRMAPK1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL1161694 | 0.77 | CDC7 (0.50) | TSHRMAPK1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL9621847 | 0.74 | L3MBTL1 (0.41) | ALDH1A1SMN1; SMN2ABCB1 | |
| SCHEMBL9267362 | 0.73 | KEAP1 (0.64) | TSHRCYP11B1CYP11B2CYP2D6CYP17A1 | |
| SCHEMBL10407004 | 0.72 | TSHR (0.43) | TSHRCYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL9193075 | 0.72 | TSHR (0.49) | TSHRCYP2D6CYP2C19CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126357-A | ANTI-INFLAMMATORY PICOLYSELENOBENZAMIDES AND SALTS THEREOF | A. NATTERMANN & CIE. GMBH (DE) | 1992-06-30 | — | — | US | disclosed |