Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11875125 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4ETSHRHPGDLMNA | |
| SCHEMBL905244 | 0.83 | ALDH1A1 (0.63) | ALDH1A1KDM4ETSHRKMT2AHSD17B10 | |
| SCHEMBL9622292 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRKMT2AHPGDLMNA | |
| Bicarbonate SCHEMBL27492793 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4ETSHRKMT2AHSD17B10 | |
| SCHEMBL6491004 | 0.81 | FTO (0.56) | ALDH1A1KDM4ETSHRKMT2AHSD17B10 | |
| SCHEMBL29817984 | 0.81 | RECQL (0.50) | ALDH1A1KDM4ETSHRKMT2AHPGD | |
| SCHEMBL1161996 | 0.81 | RECQL (0.50) | ALDH1A1KDM4ETSHRKMT2AHPGD | |
| SCHEMBL1053353 | 0.80 | L3MBTL1 (0.61) | ALDH1A1KDM4ETSHRKMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL17906582 | 0.79 | RECQL (0.49) | ALDH1A1KDM4ETSHRHPGDCYP1A2 | |
| SCHEMBL70322 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KDM4ETSHRKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994022852-A1 | QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1994-10-13 | — | — | WO | disclosed |