Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1159966 | 0.67 | LMNA (0.34) | — | |
| Hydrochloric Acid SCHEMBL9940938 | 0.58 | SLC6A2 (0.33) | — | |
| SCHEMBL1979214 | 0.58 | MEN1 (0.50) | AR | |
| SCHEMBL3841672 | 0.57 | AR (0.50) | AR | |
| SCHEMBL5182616 | 0.55 | FAAH (0.50) | AR | |
| SCHEMBL853440 | 0.55 | AR (0.49) | AR | |
| SCHEMBL1421707 | 0.55 | AR (0.57) | AR | |
| SCHEMBL5302868 | 0.55 | FAAH (0.50) | AR | |
| SCHEMBL8724660 | 0.52 | — | — | |
| SCHEMBL3649196 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110823-A | Cognition activators | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0174136-B1 | DERIVATIVES OF DIHYDRO-1H-PYRROLO(1,2-C)IMIDAZOL-3,5-DIONE AS COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY (US) | 1989-03-22 | — | — | EP | disclosed |
| US-4582838-A | FOR TREATING SENILITY OR REVERSING EFFECTS OF ELECTROCONVULSIVE SHOCK-INDUCED AMNESIA | WARNER-LAMBERT COMPANY (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0174136-A1 | Derivatives of dihydro-1H-pyrrolo(1,2-c)imidazol-3,5-dione as cognition activators | WARNER-LAMBERT COMPANY (US) | 1986-03-12 | — | — | EP | disclosed |