Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 8/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449421 | 0.87 | HTR2A (0.42) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL28618542 | 0.75 | HTR2B (0.46) | ALDH1A1HTR2CHTR2AHTR2BTRPA1 | |
| SCHEMBL30838752 | 0.75 | HTR2B (0.46) | ALDH1A1HTR2CHTR2AHTR2BTRPA1 | |
| SCHEMBL11526876 | 0.73 | HTR2A (0.40) | HTR2CHTR2AMEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL8916641 | 0.71 | MEN1 (0.34) | ALDH1A1HTR2CHTR2AHTR2BMEN1 | |
| SCHEMBL9449328 | 0.71 | HTR2A (0.42) | ALDH1A1HTR2CHTR2AHTR2BMEN1 | |
| SCHEMBL18515869 | 0.71 | HTR2A (0.42) | ALDH1A1HTR2CHTR2AHTR2BMEN1 | |
| SCHEMBL11526446 | 0.68 | HTR2A (0.33) | ALDH1A1HTR2CHTR2AHTR2BMEN1 | |
| SCHEMBL27335604 | 0.68 | HTR2A (0.44) | ALDH1A1HTR2CHTR2AHTR2BMEN1 | |
| SCHEMBL9622137 | 0.68 | MYC (0.44) | ALDH1A1HTR2CHTR2AHTR2BCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079260-A | Side effect reduction; fluorene derivatives | NOVA PHARMACEUTICAL CORPORATION (US) | 1992-01-07 | — | — | US | disclosed |
| WO-1991018596-A1 | METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN | WEITZBERG MOSHE (US) | 1991-12-12 | — | — | WO | disclosed |