Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HTR2B | P41595 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8917252 | 0.90 | HTR2A (0.42) | MEN1ALDH1A1KMT2AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL8917342 | 0.88 | HTR2A (0.36) | HTR2A | |
| Hydrochloric Acid SCHEMBL6557592 | 0.77 | HTR2A (0.36) | HTR2A | |
| SCHEMBL27335604 | 0.76 | HTR2A (0.44) | MEN1ALDH1A1KMT2AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9126330 | 0.75 | MAPT (0.40) | MEN1ALDH1A1KMT2AHTR2B | |
| Hydrochloric Acid SCHEMBL7251524 | 0.74 | MYC (0.38) | MEN1ALDH1A1KMT2AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL8918026 | 0.73 | PDE10A (0.36) | — | |
| Hydrochloric Acid SCHEMBL5352654 | 0.72 | HTR2A (0.47) | ALDH1A1HTR2A | |
| Hydrochloric Acid SCHEMBL6559419 | 0.71 | MAPT (0.35) | MEN1ALDH1A1KMT2AHTR2AHTR2B | |
| SCHEMBL17208391 | 0.71 | PBRM1 (0.40) | MEN1ALDH1A1KMT2AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668230-A | METALLOCENE WITH ETHYLENE BRIDGED FLUORENE UNITS, ALUMOXANE COCATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-09-16 | — | — | US | claimed |