Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.45 |
| ▸ | DRD2 | P14416 | 6/20 | 0.45 |
| ▸ | DRD3 | P35462 | 6/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9623206 | 0.95 | DRD4 (0.44) | DRD4DRD2DRD3 | |
| Fumaric Acid SCHEMBL9623193 | 0.95 | DRD4 (0.44) | DRD4DRD2DRD3 | |
| SCHEMBL9622510 | 0.89 | DRD4 (0.55) | DRD4DRD2DRD3 | |
| SCHEMBL9622424 | 0.84 | HTR3A (0.58) | DRD2HTR4 | |
| SCHEMBL9623046 | 0.75 | HTR3A (0.47) | DRD4DRD2DRD3HTR4 | |
| SCHEMBL9458245 | 0.72 | DRD4 (0.51) | DRD4DRD2DRD3 | |
| SCHEMBL9623163 | 0.72 | HTR3A (0.47) | DRD2HTR4 | |
| SCHEMBL9622879 | 0.72 | SMN1; SMN2 (0.49) | — | |
| SCHEMBL11084314 | 0.71 | DRD2 (0.65) | DRD4DRD2DRD3 | |
| Water SCHEMBL9623052 | 0.71 | SMN1; SMN2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137895-A | Antiemetic, anxiolytic, gastric emptying and serotonin modulating activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-08-11 | — | — | US | claimed |