Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 15/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622247 | 0.90 | MAPT (0.52) | ALDH1A1MAPTKMT2AMAPK1TDP1 | |
| SCHEMBL9622602 | 0.79 | MAPT (0.53) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL9622901 | 0.79 | L3MBTL1 (0.49) | ALDH1A1MAPTHPGDKMT2AMAPK1 | |
| SCHEMBL127397 | 0.79 | MAPT (0.57) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL9622919 | 0.78 | MAPT (0.46) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL9622892 | 0.78 | MAPT (0.56) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL6135331 | 0.77 | MAPT (0.50) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL9623030 | 0.76 | MAPT (0.52) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL9623039 | 0.74 | L3MBTL1 (0.48) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL9622222 | 0.69 | MEN1 (0.57) | ALDH1A1LMNAMAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280187-B1 | HAIR DYEING COMPOSITIONS WITH DIRECT-DYEING NITRO-DIPHENYL AMINE DERIVATIVES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-01-02 | — | — | EP | disclosed |