Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623039 | 0.92 | L3MBTL1 (0.48) | L3MBTL1KCNMA1APPPDE7AMAPT | |
| SCHEMBL9622602 | 0.86 | MAPT (0.53) | L3MBTL1KCNMA1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL127397 | 0.85 | MAPT (0.57) | L3MBTL1MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9622892 | 0.84 | MAPT (0.56) | L3MBTL1KCNMA1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9622919 | 0.84 | MAPT (0.46) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6135331 | 0.83 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9623030 | 0.82 | MAPT (0.52) | KCNMA1MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10531772 | 0.81 | L3MBTL1 (0.52) | L3MBTL1KCNMA1APPPDE7AMAPT | |
| SCHEMBL10531659 | 0.81 | L3MBTL1 (0.51) | L3MBTL1KCNMA1APPMAPTALDH1A1 | |
| SCHEMBL9622925 | 0.79 | ALDH1A1 (0.46) | L3MBTL1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280187-B1 | HAIR DYEING COMPOSITIONS WITH DIRECT-DYEING NITRO-DIPHENYL AMINE DERIVATIVES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-01-02 | — | — | EP | disclosed |