Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622892 | 0.87 | MAPT (0.56) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL9622602 | 0.85 | MAPT (0.53) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL9622919 | 0.83 | MAPT (0.46) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL9622901 | 0.82 | L3MBTL1 (0.49) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL127397 | 0.82 | MAPT (0.57) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6135331 | 0.82 | MAPT (0.50) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL9623039 | 0.81 | L3MBTL1 (0.48) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL9622925 | 0.76 | ALDH1A1 (0.46) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL9622222 | 0.76 | MEN1 (0.57) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL10530352 | 0.75 | AKR1C3 (0.71) | MAPTMEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280187-B1 | HAIR DYEING COMPOSITIONS WITH DIRECT-DYEING NITRO-DIPHENYL AMINE DERIVATIVES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-01-02 | — | — | EP | disclosed |