Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TLR3 | O15455 | 1/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.55 |
| ▸ | KIT | P10721 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622712 | 0.94 | ALDH1A1 (0.50) | KDM4EMEN1KMT2AMAPTRECQL | |
| SCHEMBL1434196 | 0.79 | ALDH1A1 (0.67) | KDM4EMEN1KMT2AMAPTPOLB | |
| SCHEMBL9623045 | 0.78 | KDM4E (0.55) | KDM4EMEN1KMT2AMAPTPOLB | |
| SCHEMBL9622618 | 0.77 | KDM4E (0.50) | KDM4EMEN1KMT2AMAPTRECQL | |
| SCHEMBL2396662 | 0.77 | KDM4E (0.72) | KDM4EMEN1KMT2AMAPTPOLB | |
| SCHEMBL31486241 | 0.75 | ALDH1A1 (0.65) | KDM4EMEN1KMT2AMAPTRAB9A | |
| SCHEMBL9623211 | 0.75 | KDM4E (0.49) | KDM4EMEN1KMT2AMAPTRECQL | |
| SCHEMBL9622716 | 0.75 | PDGFRB (0.58) | KDM4EMEN1KMT2AMAPTRECQL | |
| SCHEMBL30037086 | 0.74 | KDM4E (0.56) | KDM4EMEN1KMT2AMAPTRECQL | |
| SCHEMBL6009824 | 0.74 | MAPT (0.56) | KDM4EMEN1KMT2AMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |