SCHEMBL6009824

SCHEMBL6009824

COc1ccc2[nH]c3c(C)c(C)c(OC)c(O)c3c2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.56
KDM4E B2RXH2 4/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
RECQL P46063 2/20 0.56
RAB9A P51151 2/20 0.56
TLR3 O15455 1/20 0.56
NR3C1 P04150 1/20 0.56
POLB P06746 1/20 0.56
KIT P10721 1/20 0.56
PKM P14618 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
TDP1 Q9NUW8 1/20 0.52
ALOX5 P09917 1/20 0.51
ALDH1A1 P00352 5/20 0.50
ROCK2 O75116 4/20 0.50
HSD17B10 Q99714 2/20 0.50
PDGFRB P09619 1/20 0.50
TSHR P16473 1/20 0.50
GFER P55789 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30037086 0.87 KDM4E (0.56) MAPTKDM4EMEN1KMT2ARECQL
SCHEMBL29787105 0.85 ROCK2 (0.47) MAPTKDM4EMEN1KMT2ARECQL
SCHEMBL6009770 0.81 PARP1 (0.48) MAPTKDM4EMEN1KMT2ARECQL
SCHEMBL29774621 0.81 PARP1 (0.48) MAPTKDM4EMEN1KMT2ARECQL
SCHEMBL24276985 0.80 KIT (0.80) MAPTKDM4EMEN1KMT2ARECQL
SCHEMBL12673851 0.75 ROCK2 (0.50) MAPTKDM4EMEN1KMT2ARECQL
SCHEMBL9622950 0.74 KDM4E (0.55) MAPTKDM4EMEN1KMT2ARECQL
SCHEMBL30143971 0.73 MAPT (0.59) MAPTKDM4EMEN1KMT2ARECQL
SCHEMBL8821041 0.73 MAPT (0.59) MAPTKDM4EMEN1KMT2ARECQL
SCHEMBL29787118 0.72 MEN1 (0.46) MAPTKDM4EMEN1KMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4706683-A2 CHEWABLE FORMULATIONS Elanco Tiergesundheit AG (CH) 2026-03-11 EP disclosed
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2026-02-05 US disclosed
US-12465564-B2 Oral and nasal compositions and methods of treatment AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
US-20250339367-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-06 US disclosed
US-12403090-B2 Oral film compositions and dosage forms having precise active dissolution profiles AQUESTIVE THERAPEUTICS, INC. (US) 2025-09-02 US disclosed
US-20250255780-A1 SYSTEM AND METHOD FOR MAKING PERSONALIZED INDIVIDUAL UNIT DOSES CONTAINING PHARMACEUTICAL ACTIVES AQUESTIVE THERAPEUTICS, INC. (US) 2025-08-14 US disclosed
US-12310922-B2 System and method for making personalized individual unit doses containing pharmaceutical actives AQUESTIVE THERAPEUTICS, INC. (US) 2025-05-27 US disclosed
US-12290597-B2 Oral film compositions and dosage forms having precise active dissolution profiles AQUESTIVE THERAPEUTICS, INC. (US) 2025-05-06 US disclosed
US-12171723-B2 System and method for making personalized individual unit doses containing pharmaceutical actives AQUESTIVE THERAPEUTICS, INC. (US) 2024-12-24 US disclosed
EP-4422607-A1 ORAL AND NASAL COMPOSITIONS AND METHODS OF TREATMENT Aquestive Therapeutics, Inc. (US) 2024-09-04 EP disclosed
US-20220347117-A1 DOSAGE FORMS HAVING EQUIVALENT BIOCOMPARABLE PROFILES U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION 2022-11-03 US disclosed
EP-4058029-A1 MULTIMODAL COMPOSITIONS AND METHODS OF TREATMENT Aquestive Therapeutics, Inc. (US) 2022-09-21 EP disclosed
WO-2022192476-A1 DOSAGE FORMS HAVING EQUIVALENT BIOCOMPARABLE PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2022-09-15 WO disclosed
WO-2022187556-A1 THERAPEUTIC METHODS AND COMPOSITIONS COMPRISING MAGNETIZABLE NANOPARTICLES VRG STEM CELL SERVICES INC. (US) 2022-09-09 WO disclosed
EP-4051235-A1 PRODRUG COMPOSITIONS AND METHODS OF TREATMENT Aquestive Therapeutics, Inc. (US) 2022-09-07 EP disclosed
US-20220233471-A1 PRODRUG COMPOSITIONS AND METHODS OF TREATMENT AQUESTIVE THERAPEUTICS, INC. (US) 2022-07-28 US disclosed
WO-2022155544-A1 PRODRUG COMPOSITIONS AND METHODS OF TREATMENT AQUESTIVE THERAPEUTICS, INC. (US) 2022-07-21 WO disclosed
WO-2022049149-A1 CHEWABLE FORMULATIONS ELANCO TIERGESUNDHEIT AG (CH) 2022-03-10 WO disclosed
US-7132441-B2 Immunosuppressive effects of administration of a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor G.D. SEARLE & CO. (US) 2006-11-07 US disclosed
US-6376528-B1 SYNERGISTIC MIXTURE G. D. SEARLE & CO. 2002-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220233471-A1 PRODRUG COMPOSITIONS AND METHODS OF TREATMENT CYP2C19, PAICS, CYP2B6 MAPT 1510/4885KDM4E 3899/4885MEN1 2692/4885
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES SORD, SLC6A13, CACNA1A MAPT 97/4885KDM4E 1515/4885MEN1 2827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.