Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.46 |
| ▸ | TUBB | P07437 | 4/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623045 | 0.92 | KDM4E (0.55) | KDM4EALDH1A1GAAPOLBTDP1 | |
| SCHEMBL9623538 | 0.90 | KDM4E (0.45) | KDM4EALDH1A1GAAPOLBTDP1 | |
| SCHEMBL9622538 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1GAAPOLBTDP1 | |
| SCHEMBL9622887 | 0.81 | GABRA1 (0.45) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL9622712 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAPOLBTDP1 | |
| SCHEMBL9622950 | 0.75 | KDM4E (0.55) | KDM4EALDH1A1GAAPOLBTDP1 | |
| SCHEMBL9623171 | 0.73 | ALDH1A1 (0.45) | KDM4EALDH1A1GAAPOLBTDP1 | |
| SCHEMBL1434196 | 0.70 | ALDH1A1 (0.67) | KDM4EALDH1A1GAAPOLBTDP1 | |
| SCHEMBL31486241 | 0.70 | ALDH1A1 (0.65) | KDM4EALDH1A1GAAL3MBTL1PDGFRB | |
| SCHEMBL11733627 | 0.69 | KDM4E (0.60) | KDM4EALDH1A1GAAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |