Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4865476 | 0.83 | SMN1; SMN2 (0.43) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| SCHEMBL9622966 | 0.80 | KMT2A (0.61) | KMT2AMEN1ATMSMN1; SMN2GAA | |
| SCHEMBL31689699 | 0.77 | KMT2A (0.67) | KMT2AMEN1ATMSMN1; SMN2GAA | |
| SCHEMBL23405764 | 0.77 | KMT2A (0.67) | KMT2AMEN1ATMSMN1; SMN2GAA | |
| SCHEMBL10337118 | 0.75 | KDM4E (0.47) | KMT2AMEN1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL16765289 | 0.74 | BCHE (0.60) | KMT2AMEN1ATMSMN1; SMN2LMNA | |
| SCHEMBL16764559 | 0.74 | KMT2A (0.60) | KMT2AMEN1ATMSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL9621781 | 0.74 | KDM4E (0.46) | KMT2AMEN1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL10826146 | 0.73 | SLC2A1 (0.54) | KMT2AMEN1ATMSMN1; SMN2SLC2A1 | |
| SCHEMBL9416614 | 0.72 | LMNA (0.73) | KMT2AMEN1ATMSMN1; SMN2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238060-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS | Banyu Pharmaceutical Co., Ltd. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4814328-A | Cephalosporin derivatives, and antibacterial agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4782155-A | ISOQUINOLINE SALTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-11-01 | — | — | US | disclosed |