Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622964 | 0.83 | KMT2A (0.56) | SMN1; SMN2MEN1KMT2ATDP1LMNA | |
| Phenylacetaldehyde SCHEMBL452558 | 0.82 | LMNA (0.44) | SMN1; SMN2MEN1KMT2ATAAR1LMNA | |
| SCHEMBL3130447 | 0.81 | MEN1 (0.58) | ADH1BADH1CADH1AADH7DPP7 | |
| SCHEMBL7738687 | 0.79 | LMNA (0.39) | SMN1; SMN2MEN1KMT2ATDP1TAAR1 | |
| Phenylacetaldehyde SCHEMBL1412189 | 0.79 | LMNA (0.41) | SMN1; SMN2MEN1KMT2ATAAR1LMNA | |
| Dihydrocinnamaldehyde SCHEMBL598211 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2ATAAR1LMNA | |
| SCHEMBL11505545 | 0.77 | LMNA (0.57) | TDP1LMNAALDH1A1 | |
| SCHEMBL11185055 | 0.76 | HSD17B10 (0.48) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| Phenylacetaldehyde SCHEMBL10892064 | 0.76 | LMNA (0.39) | SMN1; SMN2MEN1KMT2ATDP1TAAR1 | |
| SCHEMBL7949742 | 0.75 | TSHR (0.42) | MEN1KMT2ATAAR1TK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245132-B1 | ENCAPSULATED BENEFIT AGENT | UNILEVER PLC NO 41424 (GB) | 2017-10-18 | — | — | EP | claimed |
| US-7345040-B2 | Reverse-turn mimetics and compositions and methods relating thereto | MYRIAD GENETICS, INC. (US) | 2008-03-18 | — | — | US | disclosed |
| US-20050250780-A1 | Reverse-turn mimetics and compositions and methods relating thereto | MYRIAD GENETICS, INCORPORATED (US) | 2005-11-10 | — | — | US | disclosed |
| WO-2004035587-A1 | REVERSE-TURN MIMETICS AND COMPOSITION AND METHODS RELATING THERETO | MYRIAD GENETICS, INC. (US) | 2004-04-29 | — | — | WO | disclosed |
| US-4137268-A | Method of preparing aminoacetaldehyde acetals by the hydrogenation of dialkoxyacetonitrile | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1979-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250780-A1 | Reverse-turn mimetics and compositions and methods relating thereto | TAC3, NTSR1, SCTR | SMN1; SMN2 3294/4885ADH1B 2805/4885ADH1C 4362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.