Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.44 |
| ▸ | WEE1 | P30291 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622455 | 0.89 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL9623034 | 0.87 | TERT (0.47) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL9623204 | 0.83 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| Bromide SCHEMBL9623289 | 0.82 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL5828276 | 0.81 | PARP1 (0.51) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL9622903 | 0.76 | PDGFRB (0.45) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL9623031 | 0.74 | PDGFRB (0.50) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL9623078 | 0.73 | TERT (0.47) | ALDH1A1TDP1KDM4EHPGDMPO | |
| SCHEMBL29351752 | 0.73 | TERT (0.47) | ALDH1A1TDP1KDM4EHPGDMPO | |
| Hydrochloric Acid SCHEMBL9623220 | 0.73 | PDGFRB (0.49) | MEN1KMT2AALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |