Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | PPOX | P50336 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6340923 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9623147 | 0.80 | TERT (0.44) | KDM4EALDH1A1HPGDHSD17B10TERT | |
| SCHEMBL2659189 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL6341593 | 0.78 | KDM4E (0.58) | KDM4EALDH1A1HPGDGLASMN1; SMN2 | |
| SCHEMBL9623333 | 0.77 | WEE1 (0.54) | TERT | |
| SCHEMBL10340123 | 0.76 | ATG4B (0.43) | — | |
| SCHEMBL4084570 | 0.76 | MEN1 (0.51) | ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9623077 | 0.76 | WEE1 (0.53) | TERT | |
| Hydrochloric Acid SCHEMBL10340135 | 0.76 | ATG4B (0.42) | — | |
| SCHEMBL10661147 | 0.75 | HTT (0.51) | KDM4EALDH1A1HPGDGLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |