Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | PPOX | P50336 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PRKCG | P05129 | 1/20 | 0.45 |
| ▸ | PRKCB | P05771 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | PRKCH | P24723 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2659189 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1HPGDPPOXCASP3 | |
| SCHEMBL9623183 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1HPGDPPOXCASP3 | |
| SCHEMBL10661147 | 0.80 | HTT (0.51) | KDM4EALDH1A1HPGDPPOXCASP3 | |
| SCHEMBL6341593 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1HPGDPPOXCASP3 | |
| SCHEMBL24237000 | 0.79 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDPPOXCASP3 | |
| SCHEMBL17145936 | 0.79 | GSK3B (0.45) | KDM4EALDH1A1HPGDPPOXCASP3 | |
| SCHEMBL11045211 | 0.76 | CASP3 (0.53) | KDM4EALDH1A1HPGDPPOXCASP3 | |
| SCHEMBL6340203 | 0.76 | APP (0.58) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL22032609 | 0.76 | MAPT (0.54) | KDM4EALDH1A1HPGDPPOXCASP3 | |
| SCHEMBL10282762 | 0.75 | KDM4E (0.59) | KDM4EALDH1A1HPGDPPOXCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | LUMINIDE | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | APEH, PAH, ALAD | KDM4E 3072/4885ALDH1A1 61/4885HPGD 413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.