Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 5/20 | 0.39 |
| ▸ | PGR | P06401 | 4/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.39 |
| ▸ | SHBG | P04278 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623240 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPK1NR3C1LMNAHIF1A | |
| SCHEMBL9624037 | 0.84 | ALDH1A1 (0.66) | ALDH1A1MAPK1NR3C1LMNAHIF1A | |
| SCHEMBL9624036 | 0.84 | ALDH1A1 (0.66) | ALDH1A1MAPK1NR3C1LMNAHIF1A | |
| SCHEMBL13069288 | 0.83 | ALDH1A1 (0.58) | ALDH1A1MAPK1NR3C1LMNAHIF1A | |
| SCHEMBL9624264 | 0.81 | CYP3A4 (0.47) | ALDH1A1MAPK1NR3C1LMNAHIF1A | |
| SCHEMBL9623139 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPK1NR3C1LMNAHIF1A | |
| SCHEMBL9624042 | 0.73 | KDM4E (0.67) | ALDH1A1MAPK1NR3C1LMNAHIF1A | |
| SCHEMBL9623710 | 0.72 | CYP3A4 (0.71) | ALDH1A1NR3C1LMNAHIF1AMEN1 | |
| SCHEMBL9623707 | 0.72 | CYP3A4 (0.71) | ALDH1A1NR3C1LMNAHIF1AMEN1 | |
| SCHEMBL10974542 | 0.72 | CYP3A4 (0.71) | ALDH1A1NR3C1LMNAHIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |