Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.41 |
| ▸ | PGR | P06401 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5943274 | 0.83 | KDM4E (0.80) | KDM4EALDH1A1MAPK1LMNAHIF1A | |
| SCHEMBL5943277 | 0.83 | KDM4E (0.80) | KDM4EALDH1A1MAPK1LMNAHIF1A | |
| SCHEMBL9624264 | 0.82 | CYP3A4 (0.47) | KDM4EALDH1A1MAPK1LMNAHIF1A | |
| SCHEMBL9624036 | 0.82 | ALDH1A1 (0.66) | KDM4EALDH1A1MAPK1LMNAHIF1A | |
| SCHEMBL9624037 | 0.82 | ALDH1A1 (0.66) | KDM4EALDH1A1MAPK1LMNAHIF1A | |
| SCHEMBL3170744 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1MAPK1LMNAHIF1A | |
| SCHEMBL5259047 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1MAPK1LMNAHIF1A | |
| SCHEMBL6152790 | 0.80 | KDM4E (0.76) | KDM4EALDH1A1MAPK1LMNAHIF1A | |
| SCHEMBL3170735 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1MAPK1LMNAHIF1A | |
| SCHEMBL3170728 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1MAPK1LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |