Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.40 |
| ▸ | CCND1 | P24385 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MYLK | Q15746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623280 | 0.86 | KDM4E (0.45) | GSK3AGSK3BNQO1PAX8MAPT | |
| SCHEMBL9622486 | 0.86 | PDGFRB (0.47) | GSK3AGSK3BNQO1PAX8ROCK2 | |
| SCHEMBL9623229 | 0.83 | CHEK1 (0.44) | ROCK2PDGFRBMAPTKMT2AMEN1 | |
| SCHEMBL9622906 | 0.81 | ROCK2 (0.44) | ROCK2SMN1; SMN2KDM4EMAOBALDH1A1 | |
| SCHEMBL9623259 | 0.81 | CHEK1 (0.43) | GSK3AGSK3BROCK2MYLKCHEK1 | |
| Hydrochloric Acid SCHEMBL9623075 | 0.80 | ROCK2 (0.43) | ROCK2SMN1; SMN2KDM4EMAOBALDH1A1 | |
| SCHEMBL9623319 | 0.80 | ROCK2 (0.48) | ROCK2PDGFRBCDK4CCND1MYLK | |
| Hydrochloric Acid SCHEMBL9622616 | 0.79 | ROCK2 (0.47) | ROCK2PDGFRBCDK4CCND1MYLK | |
| SCHEMBL9622522 | 0.78 | PDGFRB (0.46) | ROCK2PDGFRBMAPTKMT2AMEN1 | |
| SCHEMBL9622903 | 0.77 | PDGFRB (0.45) | ROCK2PDGFRBMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |