Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | PRKACG | P22612 | 1/20 | 0.40 |
| ▸ | PRKACB | P22694 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622462 | 0.86 | CHEK1 (0.45) | KDM4EALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL9623359 | 0.86 | GSK3A (0.45) | KDM4EALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL9623229 | 0.85 | CHEK1 (0.44) | KDM4EMAPTSMN1; SMN2CHEK1HTR1D | |
| SCHEMBL9622906 | 0.84 | ROCK2 (0.44) | KDM4EALDH1A1SMN1; SMN2CHEK1MAOB | |
| Hydrochloric Acid SCHEMBL9623075 | 0.84 | ROCK2 (0.43) | KDM4EALDH1A1SMN1; SMN2CHEK1MAOB | |
| SCHEMBL9622486 | 0.80 | PDGFRB (0.47) | KDM4EALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL9622994 | 0.75 | ROCK2 (0.45) | CHEK1 | |
| SCHEMBL9622827 | 0.72 | KIT (0.44) | SMN1; SMN2NPSR1CHEK1GSK3AGSK3B | |
| SCHEMBL9623324 | 0.72 | CHEK1 (0.45) | GAASMN1; SMN2NPSR1CHEK1HTR1D | |
| SCHEMBL9622522 | 0.72 | PDGFRB (0.46) | KDM4EALDH1A1MAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |