Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624003 | 0.91 | MMP8 (0.40) | MMP8MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL4289218 | 0.86 | MMP8 (0.42) | MMP8MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL4302205 | 0.85 | MMP8 (0.41) | MMP8MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL1265697 | 0.84 | CYP4F2 (0.46) | MMP8MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL15551008 | 0.84 | MMP8 (0.43) | MMP8MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL20211699 | 0.78 | MEN1 (0.53) | MMP8MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL9748657 | 0.78 | MMP8 (0.44) | MMP8MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL7111727 | 0.74 | TSHR (0.33) | ALDH1A1TSHR | |
| SCHEMBL7512223 | 0.73 | MMP8 (0.52) | MMP8MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL1036163 | 0.72 | PKM (0.50) | MMP8MEN1KMT2ACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9345678-B2 | Prostanoid receptor agonist compounds and methods of use for same | ALLERGAN, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| WO-2014164886-A1 | PROSTANOID RECEPTOR AGONIST COMPOUNDS AND THEIR USE | ALLERGAN, INC. (US) | 2014-10-09 | — | — | WO | disclosed |
| US-20140275266-A1 | PROSTANOID RECEPTOR AGONIST COMPOUNDS AND METHODS OF USE FOR SAME | ALLERGAN, INC. (US) | 2014-09-18 | — | — | US | disclosed |
| EP-0274064-B1 | 2,5,6,7-TETRANOR-18,18,19,19-TETRADEHYDRO-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4880939-A | ANTISECRETORY AGENTS, HYPOTENSIVES, ANTICOAGULANTS | TORAY INDUSTRIES (JP) | 1989-11-14 | — | — | US | disclosed |
| US-4775692-A | ANTILIPEMIC, ANTICOAGULANT, HYPOTENSIVE, ANTISECRETORY AND ANTIULCER AGENT | TORAY INDUSTRIES, INC. (JP) | 1988-10-04 | — | — | US | disclosed |
| EP-0274064-A2 | 2,5,6,7-Tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1988-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275266-A1 | PROSTANOID RECEPTOR AGONIST COMPOUNDS AND METHODS OF USE FOR SAME | PTGIR, PTGER1, PTGDR | MMP8 702/4885MEN1 4378/4885KMT2A 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.