SCHEMBL9623629

SCHEMBL9623629

Cc1cc(Oc2ccc(O)cc2)ccc1O

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.58
ESR2 Q92731 2/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
LTA4H P09960 6/20 0.54
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
TP53 P04637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ESRRA P11474 1/20 0.44
PDE10A Q9Y233 1/20 0.43
PARP10 Q53GL7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30058647 0.91 TP53 (0.54) ESR1ESR2MEN1KMT2ATP53
SCHEMBL135848 0.91 TP53 (0.54) ESR1ESR2MEN1KMT2ATP53
SCHEMBL923019 0.88 TP53 (0.46) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL3365127 0.87 LTA4H (0.56) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL4101422 0.86 LTA4H (0.54) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL23519853 0.83 ALDH1A1 (0.47) ESR1ESR2MEN1KMT2ATP53
SCHEMBL17716506 0.83 TP53 (0.46) ESR1ESR2MEN1KMT2ATP53
SCHEMBL2263840 0.82 TP53 (0.42) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL3957209 0.82 MEN1 (0.70) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL2485652 0.82 MEN1 (0.56) ESR1ESR2MEN1KMT2ALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10185237-B2 Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, image forming apparatus, and polyarylate resin MITSUBISHI CHEMICAL CORPORATION (JP) 2019-01-22 US disclosed
US-20160124327-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, IMAGE FORMING APPARATUS, AND POLYARYLATE RESIN MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-05 US disclosed
US-20160124327-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, IMAGE FORMING APPARATUS, AND POLYARYLATE RESIN MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-05 US disclosed
EP-0212944-B1 MELT-PROCESSABLE AROMATIC COPOLYESTER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-04-08 EP disclosed
EP-0446720-A2 Novel brominated phenoxy compounds and processes for their preparation Bromine Compounds Ltd. (IL) 1991-09-18 EP disclosed
EP-0446722-A1 Novel hydroxylated phenoxy compounds and process for their preparation Bromine Compounds Ltd. (IL) 1991-09-18 EP disclosed
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US disclosed
EP-0212944-A2 Melt-processable aromatic copolyester Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1987-03-04 EP disclosed