Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 12/20 | 0.49 |
| ▸ | CA2 | P00918 | 12/20 | 0.49 |
| ▸ | CA9 | Q16790 | 8/20 | 0.47 |
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047403 | 0.84 | PRMT1 (0.77) | PRMT1ATMCA1CA2CA9 | |
| SCHEMBL28121835 | 0.82 | CA1 (0.72) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL1102000 | 0.82 | ATM (0.74) | PRMT1ATMCA1CA2CA9 | |
| SCHEMBL30699954 | 0.82 | PRMT1 (0.54) | PRMT1ATMCA1CA2CA9 | |
| SCHEMBL12113370 | 0.81 | KMT2A (0.54) | PRMT1ATMMMP2MMP14CA1 | |
| SCHEMBL10946868 | 0.79 | CA1 (0.71) | PRMT1ATMCA1CA2CA9 | |
| SCHEMBL8876305 | 0.77 | ALDH1A1 (0.58) | KMT2AMEN1 | |
| SCHEMBL8247039 | 0.77 | ALDH1A1 (0.48) | PRMT1ATMMMP1MMP2MMP9 | |
| SCHEMBL9391202 | 0.76 | GSTO1 (0.55) | KMT2AMEN1 | |
| SCHEMBL1034515 | 0.76 | NPC1 (0.59) | PRMT1CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178581-B1 | Use of 2-[(2-bromo-6-fluorophenyl)imino]imidazolidine as a sedative | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1992-01-22 | — | — | EP | disclosed |
| US-4624960-A | 2-112-BROMO-6-FLUOROPHENYLIMINOIMIDAZOLIDINE | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1986-11-25 | — | — | US | disclosed |
| EP-0178581-A2 | Use of 2-[(2-bromo-6-fluorophenyl)imino]imidazolidine as a sedative | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1986-04-23 | — | — | EP | disclosed |