Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.42 |
| ▸ | AR | P10275 | 5/20 | 0.42 |
| ▸ | PGR | P06401 | 4/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | SHBG | P04278 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624281 | 0.89 | NR3C1 (0.43) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL8940232 | 0.82 | NR3C1 (0.60) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL9623805 | 0.82 | NR3C1 (0.60) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL11314335 | 0.80 | NR3C1 (0.56) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL11699208 | 0.80 | NR3C1 (0.56) | NR3C1ARPGRCYP19A1LMNA | |
| SCHEMBL11699198 | 0.80 | NR3C1 (0.56) | NR3C1ARPGRCYP19A1LMNA | |
| SCHEMBL11699233 | 0.80 | NR3C1 (0.49) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL11699239 | 0.80 | NR3C1 (0.49) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL9623073 | 0.80 | NR3C1 (0.39) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL9623817 | 0.79 | NR3C1 (0.42) | NR3C1ARPGRNR3C2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |