Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9168406 | 0.83 | KDM4E (0.40) | MEN1MAPTHPGDKMT2AGABRA1 | |
| SCHEMBL8772734 | 0.83 | SRD5A1 (0.41) | MTNR1APLA2G2ASRD5A1MEN1MAPT | |
| SCHEMBL28274016 | 0.75 | SRD5A1 (0.46) | MTNR1APLA2G2ASRD5A1MEN1MAPT | |
| SCHEMBL2214596 | 0.75 | MAPT (0.36) | MAPTLMNAHTTALDH1A1GAA | |
| SCHEMBL9168647 | 0.74 | PTPN1 (0.39) | MEN1HPGDKMT2AALDH1A1KDM4E | |
| SCHEMBL9623290 | 0.74 | XDH (0.38) | MEN1MAPTHPGDKMT2ALMNA | |
| SCHEMBL10693944 | 0.73 | SRD5A1 (0.45) | MTNR1ASRD5A1MEN1MAPTHPGD | |
| SCHEMBL10425161 | 0.72 | ESR1 (0.51) | MTNR1ASRD5A1MEN1MAPTKMT2A | |
| SCHEMBL6936437 | 0.71 | HPGD (0.48) | MTNR1APLA2G2ASRD5A1MEN1MAPT | |
| SCHEMBL4075526 | 0.71 | ACHE (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350386-B1 | UNSATURATED DERIVATIVES OF LIPID SOLUBLE BENZAL MALONATES, AND THEIR USE AS UV ABSORBERS IN THE COSMETIC FIELD | L'OREAL (FR) | 1992-04-08 | — | — | EP | claimed |
| JP-2059541-A | — | — | None | — | — | JP | disclosed |
| JP-H0259541-A | ULTRAVIOLET RADIATION ABSORBER | L'OREAL SA | 1990-02-28 | — | — | JP | disclosed |