Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 7/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245100 | 0.82 | TDP1 (0.49) | MAPTTDP1DRD2TPMTHTT | |
| SCHEMBL1940681 | 0.80 | HMGCR (0.47) | MAPTTDP1DRD2HMGCRTRPV1 | |
| SCHEMBL9053891 | 0.80 | TDP1 (0.42) | MAPTTDP1LMNAHTTSMN1; SMN2 | |
| SCHEMBL3360767 | 0.78 | HMGCR (0.40) | MAPTTDP1HMGCRTPMTLMNA | |
| Hydrochloric Acid SCHEMBL7999971 | 0.76 | NNMT (0.38) | MAPTTDP1DRD2TRPV1HTT | |
| SCHEMBL9623697 | 0.75 | MTNR1A (0.37) | MAPTLMNAHTTNPSR1ALDH1A1 | |
| SCHEMBL29157723 | 0.75 | CA12 (0.51) | MAPTALDH1A1TSHRCA12CA1 | |
| SCHEMBL29084361 | 0.74 | ALDH1A1 (0.40) | MAPTTDP1DRD2TRPV1HTT | |
| SCHEMBL4075526 | 0.73 | ACHE (0.32) | — | |
| SCHEMBL2211640 | 0.72 | MAPT (0.34) | MAPTTDP1DRD2TRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1952843-B1 | Photostable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom | MERCK PATENT GMBH (DE) | 2011-07-27 | — | — | EP | claimed |