Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24303347 | 0.83 | TDP2 (0.48) | TDP2NSD2HSP90AA1PAX8KDM4E | |
| SCHEMBL31688086 | 0.73 | TDP1 (0.50) | — | |
| SCHEMBL4715603 | 0.73 | TDP1 (0.50) | — | |
| SCHEMBL9624832 | 0.73 | KDM4E (0.65) | KDM4EHSD17B10 | |
| SCHEMBL14490216 | 0.70 | TDP2 (0.54) | TDP2NSD2HSP90AA1PAX8KDM4E | |
| SCHEMBL3280286 | 0.68 | TDP2 (0.52) | TDP2NSD2HSP90AA1PAX8KDM4E | |
| SCHEMBL17300613 | 0.67 | ELANE (0.49) | TDP2NSD2HSP90AA1PAX8KDM4E | |
| SCHEMBL12948364 | 0.67 | POLB (0.56) | — | |
| SCHEMBL12948439 | 0.67 | S100A4 (0.49) | — | |
| SCHEMBL12235606 | 0.66 | TDP2 (0.48) | TDP2NSD2HSP90AA1PAX8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116986-A | HETEROAROMATIC AMINE DERIVATIVES | DR. KARL THOMAE GMBH (DE) | 1992-05-26 | — | — | US | disclosed |
| US-4912115-A | Cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1990-03-27 | — | — | US | disclosed |