Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623132 | 0.93 | CA2 (0.48) | TP53CA2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL8813253 | 0.85 | TP53 (0.44) | TP53CA2ALDH1A1TDP1LMNA | |
| SCHEMBL23666683 | 0.84 | CA2 (0.42) | TP53CA2LMNAOPRM1FAAH | |
| SCHEMBL8813255 | 0.83 | TP53 (0.52) | TP53CA2ALDH1A1TDP1LMNA | |
| SCHEMBL28409630 | 0.82 | TP53 (0.50) | TP53CA2ALDH1A1TDP1LMNA | |
| SCHEMBL28338902 | 0.82 | TP53 (0.50) | TP53CA2ALDH1A1TDP1LMNA | |
| SCHEMBL5961183 | 0.81 | GCLC (0.36) | CA2 | |
| SCHEMBL1094064 | 0.81 | ALDH1A1 (0.52) | TP53CA2ALDH1A1TDP1LMNA | |
| SCHEMBL252431 | 0.81 | ALDH1A1 (0.57) | TP53CA2ALDH1A1TDP1LMNA | |
| SCHEMBL20223453 | 0.78 | CA2 (0.47) | TP53CA2ALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110902-A | High molecular weight polythioether-sulfones | PHILLIPS PETROLEUM COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5086163-A | High molecular weight polymers formed by contacting dihaloaromatic sulfone with complex of alkali metal aminoalkanoate and alkalimetal hydrosulfide | PHILLIPS PETROLEUM COMPANY (US) | 1992-02-04 | — | — | US | disclosed |
| US-5015725-A | Heat resistant thermoplastic resins for electrical components, aircraft or automobile parts, protective coatings | PHILLIPS PETROLEUM COMPANY (US) | 1991-05-14 | — | — | US | disclosed |
| EP-0309955-A1 | Aromatic sulfide/sulfone polymer production | PHILLIPS PETROLEUM COMPANY (US) | 1989-04-05 | — | — | EP | disclosed |
| US-4125525-A | Aromatic sulfide/sulfone polymer production | PHILLIPS PETROLEUM COMPANY (US) | 1978-11-14 | — | — | US | disclosed |