Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28409630 | 1.00 | TP53 (0.50) | TP53LMNAS1PR2S1PR1S1PR3 | |
| SCHEMBL8813255 | 0.98 | TP53 (0.52) | TP53LMNAS1PR2S1PR1S1PR3 | |
| SCHEMBL28414215 | 0.92 | TP53 (0.50) | TP53LMNAS1PR2S1PR1S1PR3 | |
| SCHEMBL9342210 | 0.92 | CA2 (0.50) | TP53LMNAS1PR2S1PR1S1PR3 | |
| SCHEMBL27915805 | 0.92 | LMNA (0.50) | TP53LMNAS1PR2S1PR1S1PR3 | |
| SCHEMBL503545 | 0.90 | LMNA (0.48) | TP53LMNAS1PR2S1PR1S1PR3 | |
| SCHEMBL10784604 | 0.84 | LMNA (0.50) | TP53LMNAS1PR2S1PR1S1PR3 | |
| SCHEMBL21659085 | 0.84 | LMNA (0.50) | TP53LMNAS1PR2S1PR1S1PR3 | |
| SCHEMBL30544586 | 0.84 | LMNA (0.42) | TP53LMNAS1PR2S1PR1S1PR3 | |
| SCHEMBL29714065 | 0.84 | CA2 (0.38) | TP53LMNAS1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793238-B | Substituted benzamides and methods of use thereof | 基因泰克公司 | 2019-12-24 | — | — | CN | disclosed |