SCHEMBL9624322

SCHEMBL9624322

NC(=O)c1c(O)c(C(=O)O)cc2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.59
GPR35 Q9HC97 2/20 0.59
ME2 P23368 1/20 0.57
ME1 P48163 1/20 0.57
ME3 Q16798 1/20 0.57
CYP2D6 P10635 1/20 0.56
MEN1 O00255 5/20 0.55
KMT2A Q03164 5/20 0.55
HSD17B10 Q99714 4/20 0.55
HPGD P15428 3/20 0.55
KDM4E B2RXH2 3/20 0.55
ALDH1A1 P00352 3/20 0.55
CYP1A2 P05177 1/20 0.55
GLA P06280 1/20 0.55
CYP2C19 P33261 1/20 0.55
CYP2C9 P11712 2/20 0.50
LDHA P00338 1/20 0.50
THRB P10828 1/20 0.50
TSHR P16473 1/20 0.50
ALOX12 P18054 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5380957 0.88 ME2 (0.70) POLBGPR35ME2ME1ME3
SCHEMBL6535489 0.83 CYP2D6 (0.60) POLBGPR35ME2ME1ME3
SCHEMBL11425630 0.82 KDM4E (0.48) POLBGPR35ME2ME1ME3
SCHEMBL3391301 0.80 POLB (0.69) POLBGPR35ME2ME1ME3
SCHEMBL11170188 0.80 POLB (0.72) POLBGPR35ME2ME1ME3
SCHEMBL1224667 0.79 POLB (0.63) POLBGPR35ME2ME1ME3
SCHEMBL10499754 0.79 KDM4E (0.55) POLBGPR35ME2ME1ME3
SCHEMBL989695 0.79 POLB (0.67) POLBGPR35ME2ME1ME3
SCHEMBL5553181 0.79 MEN1 (0.49) MEN1KMT2AHSD17B10HPGDKDM4E
SCHEMBL4579547 0.78 CDC25B (0.50) MEN1KMT2AHSD17B10KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4321373-A 2-Hydroxy-3-naphthoic acid amides HOECHST AKTIENGESELLSCHAFT (DE) 1982-03-23 US claimed
EP-0004574-B1 2-HYDROXY-3-NAPHTHALENE CARBOXAMIDES AND THEIR USE AS COUPLING AGENTS IN DIAZOTYPE MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-30 EP claimed
JP-60190386-A None JP disclosed
EP-0242886-B1 LIGHT-SENSITIVE MATERIAL CONTAINING SILVER HALIDE, REDUCING AGENT AND POLYMERIZABLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1992-03-11 EP disclosed
US-4927730-A Light-sensitive material containing silver halide, reducing agent and polymerizable compound FUJI PHOTO FILM CO., LTD. (JP) 1990-05-22 US disclosed
EP-0242886-A2 Light-sensitive material containing silver halide, reducing agent and polymerizable compound FUJI PHOTO FILM CO., LTD. (JP) 1987-10-28 EP disclosed
JP-S60190386-A THERMAL RECORDING MATERIAL RICOH CO LTD 1985-09-27 JP disclosed
US-4492749-A PHOTOSTABILITY HOECHST AKTIENGESELLSCHAFT (DE) 1985-01-08 US disclosed
US-4334004-A Light-sensitive diazotype material with 2-hydroxy-3-naphthoic acid amides having 6-sulfonic acid amide substitution HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-08 US disclosed
US-4334004-A Light-sensitive diazotype material with 2-hydroxy-3-naphthoic acid amides having 6-sulfonic acid amide substitution HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-08 US disclosed
US-4334004-A Light-sensitive diazotype material with 2-hydroxy-3-naphthoic acid amides having 6-sulfonic acid amide substitution HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-08 US disclosed
US-4321373-A 2-Hydroxy-3-naphthoic acid amides HOECHST AKTIENGESELLSCHAFT (DE) 1982-03-23 US disclosed
US-4321373-A 2-Hydroxy-3-naphthoic acid amides HOECHST AKTIENGESELLSCHAFT (DE) 1982-03-23 US disclosed
US-4321373-A 2-Hydroxy-3-naphthoic acid amides HOECHST AKTIENGESELLSCHAFT (DE) 1982-03-23 US disclosed
US-4273850-A 2,5-DIALKOXY-4-ARYLMERCAPTOBENZENE DIAZONIUM SALTS AND A HYDROXYNAPHTHALENE DISULFONAMIDE COUPLER HOECHST AKTIENGESELLSCHAFT (DE) 1981-06-16 US disclosed
US-4143034-A LIGHTFAST STERLING DRUG INC. (US) 1979-03-06 US disclosed