Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | CRBN | Q96SW2 | 9/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | IL1B | P01584 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538199 | 0.85 | TSHR (0.49) | TSHRCYP1A2ALDH1A1CYP2C9MAPT | |
| SCHEMBL11544600 | 0.77 | KDM4E (0.51) | TSHRCYP1A2ALDH1A1CYP2C9MAPT | |
| SCHEMBL7284377 | 0.76 | CRBN (0.55) | TSHRCRBNDDB1CYP1A2IKZF3 | |
| SCHEMBL22623717 | 0.76 | CRBN (0.55) | TSHRCRBNDDB1CYP1A2IKZF3 | |
| SCHEMBL410243 | 0.76 | CRBN (0.55) | TSHRCRBNDDB1CYP1A2IKZF3 | |
| SCHEMBL442296 | 0.76 | CRBN (0.55) | TSHRCRBNDDB1CYP1A2IKZF3 | |
| SCHEMBL410700 | 0.76 | CRBN (0.55) | TSHRCRBNDDB1CYP1A2IKZF3 | |
| SCHEMBL986701 | 0.75 | DDB1 (0.46) | TSHRCRBNDDB1CYP1A2IKZF3 | |
| SCHEMBL11606116 | 0.75 | DDB1 (0.46) | TSHRCRBNDDB1CYP1A2IKZF3 | |
| SCHEMBL20258195 | 0.72 | CYP1A2 (0.47) | TSHRCRBNDDB1CYP1A2IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024697-A1 | INTERMEDIATES FOR SYNTHESIZING EXATECAN MESYLATE | SIGMA-ALDRICH CO. LLC (US) | 2025-01-30 | — | — | WO | claimed |
| WO-2025024697-A1 | INTERMEDIATES FOR SYNTHESIZING EXATECAN MESYLATE | SIGMA-ALDRICH CO. LLC (US) | 2025-01-30 | — | — | WO | disclosed |
| EP-0265412-B1 | 2-AMINO-4-PHOSPHONYL-BUTANOATE DERIVATES AND PREPARATION OF 2-AMINO-4-PHOSPHINYL BUTANOIC ACIDS | Monsanto Company (US) | 1992-03-11 | — | — | EP | disclosed |
| US-4764620-A | 4-phosphorus-2-phthalimidobutyrate intermediates | MONSANTO COMPANY (US) | 1988-08-16 | — | — | US | disclosed |
| EP-0265412-A2 | 2-Amino-4-Phosphonyl-butanoate derivates and preparation of 2-amino-4-phosphinyl butanoic acids | Monsanto Company (US) | 1988-04-27 | — | — | EP | disclosed |
| US-4237305-A | INTERMEDIATES FOR PREPARING NEW ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-12-02 | — | — | US | disclosed |
| US-4118511-A | Aryloxy aminobutanols for alleviating symptoms of depression | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-10-03 | — | — | US | disclosed |
| US-4071552-A | Aryloxy aminobutanols, their preparation and use thereof | AYERST MCKENNA AND HARRISON LTD. (CA) | 1978-01-31 | — | — | US | disclosed |