SCHEMBL442296

SCHEMBL442296

O=C1CC[C@H](N2C(=O)c3ccccc3C2=O)C(=O)O1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 17/20 0.55
DDB1 Q16531 15/20 0.55
IKZF3 Q9UKT9 2/20 0.55
ALDH1A1 P00352 1/20 0.55
CHRM2 P08172 1/20 0.55
OPRM1 P35372 1/20 0.55
CYP1A2 P05177 1/20 0.55
TSHR P16473 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
TNF P01375 1/20 0.43
IL1B P01584 1/20 0.43
TBXA2R P21731 1/20 0.43
IKZF1 Q13422 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL410243 1.00 CRBN (0.55) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL410700 1.00 CRBN (0.55) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL7284377 1.00 CRBN (0.55) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL20075961 0.84 GAA (0.46) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL10074225 0.84 DDB1 (0.61) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL11606116 0.83 DDB1 (0.46) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL986701 0.83 DDB1 (0.46) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL14601082 0.80 DDB1 (0.44) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL14377303 0.79 DDB1 (0.65) CRBNDDB1IKZF3ALDH1A1CYP1A2
SCHEMBL15930060 0.79 DDB1 (0.65) CRBNDDB1IKZF3ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119529118-A Glutamic acid esterified cellulose, composite fiber, and preparation methods and applications thereof 武汉纺织大学 2025-02-28 CN claimed
CN-119306640-A Gamma-glutamyl transpeptidase detection substrate and preparation method and application thereof 英科新创(厦门)科技股份有限公司 2025-01-14 CN claimed
CN-113045446-A Preparation method of transpeptidase biochemical test reagent substrate 合肥金锦生物科技有限公司 2021-06-29 CN claimed
US-8193156-B1 Dipeptides incorporating selenoamino acids with enhanced bioavailability—synthesis, pharmaceutical and cosmeceutical applications thereof SAMI LABS LTD 2012-06-05 US claimed
US-8003614-B2 Dipeptides incorporating selenoamino acids with enhanced bioavailability—synthesis, pharmaceutical and cosmeceutical applications thereof SAMI LABS LTD (US) 2011-08-23 US claimed
US-20080026017-A1 Novel Dipeptides incorporating selenoamino acids with enhanced bioavailability- Synthesis, pharmaceutical and cosmeceutical applications thereof SAMI LABS LIMITED (IN) 2008-01-31 US claimed
EP-1144436-B1 METHOD FOR PREPARING BICYCLIC COMPOUNDS AND USE OF SAID METHOD FOR PREPARING AN INTERLEUKIN-1(Beta) CONVERSION ENZYME (ICE) INHIBITOR AVENTIS PHARMA SA (FR) 2004-04-07 EP claimed
US-6512111-B1 A method for preparing compounds of formula (I) ) wherein cyclization is carried out in a basic medium and in the presence of a phosphonic acid derivative and the use of said method as an intermediate step for preparing a compound AVENTIS PHARMA S.A. (FR) 2003-01-28 US claimed
EP-0230985-B1 GAMMA-GLUTAMYL-4-AZOANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE DETERMINATION OF GAMMA-GLUTAMYLTRANSFERASE Roche Diagnostics GmbH (DE) 1990-08-01 EP claimed
JP-55099199-A None JP disclosed
JP-62260827-A None JP disclosed
JP-56097260-A None JP disclosed
JP-1110654-A None JP disclosed
JP-57050963-A None JP disclosed
US-4177109-A BY OXIDATION AND COLOIMETRIC ANALYSIS OF LIBERATED P-PHENYLENEDIAMINE DERIVATIVE WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1979-12-04 US disclosed
US-4167449-A Composition and method for determining transferase and protease activity AMERICAN HOSPITAL SUPPLY CORPORATION (US) 1979-09-11 US disclosed
US-4076840-A TREATMENT OF ALCOHOLISM ASTRA LAKEMEDEL AKTIEBOLAG (SW) 1978-02-28 US disclosed
US-4049702-A DIAGNOSIS OF LIVER DISEASE BY DETERMINATION OF G-GLUTAMYL-TRANS-PEPTIDASE BOEHRINGER MANNHEIM G.M.B.H. (DT) 1977-09-20 US disclosed
US-3986931-A γ-GLUTAMYL-4-NITROANILIDE COMPOUNDS AND THEIR USE IN DETERMINING γ-GLUTAMYL TRANSPEPTIDASE BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-10-19 US disclosed
US-3979447-A DETERMINATION OF G-GLUTAMYLTRANSPEPTIDASE BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080026017-A1 Novel Dipeptides incorporating selenoamino acids with enhanced bioavailability- Synthesis, pharmaceutical and cosmeceutical applications thereof SCLY, CYP2R1, SPR CRBN 4149/4885DDB1 1641/4885IKZF3 1757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.