Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 4/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991564 | 0.87 | IDH1 (0.45) | IDH1MMP3BCL2MCL1PTGS1 | |
| SCHEMBL15578472 | 0.82 | IDH1 (0.44) | IDH1MMP3BCL2MCL1PTGS1 | |
| SCHEMBL6991694 | 0.78 | IDH1 (0.45) | IDH1MMP3BCL2MCL1PTGS1 | |
| SCHEMBL8274787 | 0.75 | IDH1 (0.46) | IDH1MMP3BCL2MCL1PTGS1 | |
| SCHEMBL8398573 | 0.74 | TEAD4 (0.51) | KDM4EPOLBGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL2117322 | 0.72 | IDH1 (0.41) | IDH1MMP3BCL2MCL1PTGS1 | |
| SCHEMBL8397201 | 0.69 | MMP2 (0.47) | MMP3BCL2MCL1PTGS1PTGS2 | |
| SCHEMBL2606810 | 0.69 | IDH1 (0.41) | IDH1MMP3BCL2MCL1PTGS1 | |
| SCHEMBL5315829 | 0.68 | MMP2 (0.49) | MMP3BCL2MCL1PTGS1PTGS2 | |
| SCHEMBL9625165 | 0.68 | MMP2 (0.43) | IDH1MMP3BCL2MCL1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473764-A1 | METAL COMPLEXES | Hider, Robert Charles (GB) | 1992-03-11 | — | — | EP | claimed |
| WO-1991014664-A1 | METAL COMPLEXES | HIDER ROBERT CHARLES (GB) | 1991-10-03 | — | — | WO | claimed |
| EP-0473764-A1 | METAL COMPLEXES | Hider, Robert Charles (GB) | 1992-03-11 | — | — | EP | disclosed |
| WO-1991014664-A1 | METAL COMPLEXES | HIDER ROBERT CHARLES (GB) | 1991-10-03 | — | — | WO | disclosed |