SCHEMBL9625501

SCHEMBL9625501

O=S(=O)(c1ccc(Oc2ccc(-c3ccccc3)cc2)cc1)c1ccc(Oc2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
SOS1 Q07889 1/20 0.57
BCL2L1 Q07817 3/20 0.55
MCL1 Q07820 3/20 0.55
HTR6 P50406 1/20 0.52
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA9 Q16790 3/20 0.52
CA12 O43570 1/20 0.52
LMNA P02545 2/20 0.52
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALDH1A1 P00352 2/20 0.48
PKM P14618 1/20 0.48
ADAMTS4 O75173 1/20 0.48
MMP2 P08253 1/20 0.47
MMP3 P08254 1/20 0.47
MMP9 P14780 1/20 0.47
MMP8 P22894 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28423763 0.96 HTT (0.67) HTTSMN1; SMN2SOS1BCL2L1MCL1
SCHEMBL9452130 0.96 HTT (0.72) HTTSMN1; SMN2SOS1BCL2L1MCL1
Biphenyl SCHEMBL1071652 0.94 HTT (0.70) HTTSMN1; SMN2SOS1BCL2L1MCL1
SCHEMBL17827515 0.91 PKM (0.66) HTTSMN1; SMN2ALDH1A1PKMMMP2
SCHEMBL21155199 0.91 HTT (0.57) HTTSMN1; SMN2SOS1BCL2L1MCL1
SCHEMBL6848913 0.89 HTT (0.74) HTTSMN1; SMN2SOS1HTR6CA1
SCHEMBL146566 0.89 HTT (0.81) HTTSMN1; SMN2SOS1HTR6CA1
SCHEMBL17559302 0.89 HTT (0.81) HTTSMN1; SMN2SOS1HTR6CA1
SCHEMBL6123058 0.89 HTT (0.81) HTTSMN1; SMN2SOS1HTR6CA1
SCHEMBL11415437 0.89 HTT (0.81) HTTSMN1; SMN2SOS1HTR6CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0266497-A1 Wholly aromatic polyester composition and process for producing it TEIJIN LIMITED (JP) 1988-05-11 EP claimed
JP-3095231-A None JP disclosed
JP-60069132-A None JP disclosed
WO-1992007894-A1 ETHER-KETONE-SULPHONE COPOLYMERS RAYCHEM LIMITED (GB) 1992-05-14 WO disclosed
EP-0210851-B1 Mixtures of polyamideimides, containing 3,4'-diaminodiphenylether as diamine component, and of a plasticizer. TEIJIN LIMITED (JP) 1992-03-18 EP disclosed
EP-0423220-A1 ETHERSULPHONE POLYMERS RAYCHEM LIMITED (GB) 1991-04-24 EP disclosed
JP-H0395231-A MANUFACTURE OF WHOLLY AROMATIC POLYESTER MOLDING TEIJIN LTD 1991-04-19 JP disclosed
WO-1990000573-A1 ETHERSULPHONE POLYMERS RAYCHEM LIMITED (GB) 1990-01-25 WO disclosed
EP-0266497-A1 Wholly aromatic polyester composition and process for producing it TEIJIN LIMITED (JP) 1988-05-11 EP disclosed
EP-0070539-B1 PROCESS FOR PRODUCING A FILM-LIKE AND FIBROUS ARTICLE OF A WHOLLY AROMATIC POLYESTER TEIJIN LIMITED (JP) 1987-07-01 EP disclosed
EP-0156966-A1 Wholly aromatic polyester composition and process for producing it TEIJIN LIMITED (JP) 1985-10-09 EP disclosed
JP-S6069132-A FULLY AROMATIC POLYESTER, ITS MOLDING COMPOSITION AND PRODUCTION OF MOLDING USING SAME TEIJIN LTD 1985-04-19 JP disclosed
US-4416839-A Wholly aromatic polyester composition, process for production thereof, and production therefrom of a film-like or fibrous article of a wholly aromatic polyester TEIJIN LIMITED (JP) 1983-11-22 US disclosed
EP-0070539-A1 Process for producing a film-like and fibrous article of a wholly aromatic polyester TEIJIN LIMITED (JP) 1983-01-26 EP disclosed
JP-H00395231-A 0001-01-01 JP disclosed