Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.64 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624151 | 0.86 | SMN1; SMN2 (0.57) | ALDH1A1KMT2AMEN1GRIN1GRIN2B | |
| SCHEMBL9625948 | 0.86 | SMN1; SMN2 (0.57) | ALDH1A1KMT2AMEN1GRIN1GRIN2B | |
| SCHEMBL2018003 | 0.78 | GRIN1 (1.00) | KMT2AMEN1GRIN1GRIN2BPOLB | |
| SCHEMBL2017472 | 0.78 | GRIN1 (0.74) | ALDH1A1KMT2AMEN1GRIN1GRIN2B | |
| SCHEMBL8701414 | 0.78 | NPC1 (0.68) | ALDH1A1KMT2AMEN1POLBTSHR | |
| SCHEMBL9625696 | 0.77 | LTA4H (0.58) | ALDH1A1GAAHPGDLMNATDP1 | |
| SCHEMBL9625327 | 0.77 | LTA4H (0.58) | ALDH1A1GAAHPGDLMNATDP1 | |
| Hydrochloric Acid SCHEMBL9440277 | 0.77 | HTR2A (0.52) | KMT2AMEN1GRIN1GRIN2BPOLB | |
| SCHEMBL8392932 | 0.77 | POLB (0.67) | ALDH1A1KMT2AMEN1POLBTSHR | |
| SCHEMBL9625624 | 0.76 | NPC1 (0.50) | ALDH1A1KMT2AMEN1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155268-A | Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides | THE UPJOHN COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0164865-B1 | N-(AMINOALKYLPHENYL)SULFONAMIDES THEIR PREPARATION AND THERAPEUTIC USE | THE UPJOHN COMPANY (US) | 1988-12-21 | — | — | EP | disclosed |
| EP-0164865-A1 | N-(Aminoalkylphenyl)sulfonamides their preparation and therapeutic use | THE UPJOHN COMPANY (US) | 1985-12-18 | — | — | EP | disclosed |