SCHEMBL9625632

SCHEMBL9625632

CC1(C)CC(N2C(=O)c3ccccc3C2=O)CC(C)(CN2C(=O)c3ccccc3C2=O)C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
CYP1A2 P05177 2/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
TSHR P16473 3/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
ACHE P22303 2/20 0.37
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
RPS6KA2 Q15349 1/20 0.35
CHRM2 P08172 1/20 0.35
OPRM1 P35372 1/20 0.35
DDB1 Q16531 1/20 0.35
CRBN Q96SW2 1/20 0.35
IKZF3 Q9UKT9 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14417944 0.82 POLB (0.50) ALDH1A1TSHRNPSR1MEN1GAA
SCHEMBL14928448 0.81 CYP1A2 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19ACHE
SCHEMBL21162508 0.78 HSD11B1 (0.30) ALDH1A1
SCHEMBL11035277 0.76 TSHR (0.43) ALDH1A1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL24541445 0.74 CNR2 (0.31) ALDH1A1
SCHEMBL26452099 0.73 LPAR1 (0.35) ALDH1A1MEN1KMT2ATDP1
SCHEMBL3048785 0.73 ALDH1A1 (0.45) ALDH1A1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL10909961 0.73 L3MBTL1 (0.38) ALDH1A1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL17532455 0.73 MEN1 (0.31) TSHRMEN1KMT2A
SCHEMBL21357682 0.71 CNR2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58210934-A None JP disclosed
EP-0210851-B1 Mixtures of polyamideimides, containing 3,4'-diaminodiphenylether as diamine component, and of a plasticizer. TEIJIN LIMITED (JP) 1992-03-18 EP disclosed
EP-0156966-B1 WHOLLY AROMATIC POLYESTER COMPOSITION AND PROCESS FOR PRODUCING IT TEIJIN LIMITED (JP) 1988-10-19 EP disclosed
EP-0070539-B1 PROCESS FOR PRODUCING A FILM-LIKE AND FIBROUS ARTICLE OF A WHOLLY AROMATIC POLYESTER TEIJIN LIMITED (JP) 1987-07-01 EP disclosed
EP-0091669-B1 PROCESS FOR PRODUCING POROUS, FILM-LIKE OR FIBROUS STRUCTURE OF AROMATIC POLYESTER TEIJIN LIMITED (JP) 1986-10-01 EP disclosed
EP-0057387-B1 PRODUCTION OF A FILM-LIKE OR FIBROUS STRUCTURE OF AN AROMATIC POLYESTER TEIJIN LIMITED (JP) 1986-05-07 EP disclosed
EP-0156966-A1 Wholly aromatic polyester composition and process for producing it TEIJIN LIMITED (JP) 1985-10-09 EP disclosed
US-4517315-A Production of a film-like or fibrous structure of an aromatic polyester TEIJIN LIMITED (JP) 1985-05-14 US disclosed
JP-S58210934-A PREPARATION OF POROUS MOLDED ARTICLE OF POLYESTER TEIJIN LTD 1983-12-08 JP disclosed
US-4419308-A SOLVENT EXTRACTION OF IMIDE OR ISOCYANURATE TEIJIN LIMITED (JP) 1983-12-06 US disclosed
US-4416839-A Wholly aromatic polyester composition, process for production thereof, and production therefrom of a film-like or fibrous article of a wholly aromatic polyester TEIJIN LIMITED (JP) 1983-11-22 US disclosed
EP-0091669-A2 Process for producing porous, film-like or fibrous structure of aromatic polyester TEIJIN LIMITED (JP) 1983-10-19 EP disclosed
EP-0070539-A1 Process for producing a film-like and fibrous article of a wholly aromatic polyester TEIJIN LIMITED (JP) 1983-01-26 EP disclosed
EP-0057387-A2 Production of a film-like or fibrous structure of an aromatic polyester TEIJIN LIMITED (JP) 1982-08-11 EP disclosed