Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD5 | P21918 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624768 | 0.97 | SMN1; SMN2 (0.49) | SMN1; SMN2DRD2DRD5DRD3HTR1A | |
| SCHEMBL9624884 | 0.92 | SMN1; SMN2 (0.51) | SMN1; SMN2DRD2DRD5DRD3HTR1A | |
| SCHEMBL9625527 | 0.83 | L3MBTL1 (0.38) | SMN1; SMN2MAOBHDAC6 | |
| SCHEMBL9624619 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2 | |
| SCHEMBL9624246 | 0.80 | HCN4 (0.46) | DRD2DRD5DRD3HTR1AHTR7 | |
| SCHEMBL9624441 | 0.80 | L3MBTL1 (0.37) | SMN1; SMN2HDAC6 | |
| Hydrochloric Acid SCHEMBL9624740 | 0.79 | ALOX15 (0.47) | DRD2DRD5DRD3HTR1AHTR7 | |
| SCHEMBL9625089 | 0.79 | HDAC6 (0.37) | SMN1; SMN2KDM4EMAOBHDAC6ACHE | |
| SCHEMBL9624134 | 0.78 | L3MBTL1 (0.38) | SMN1; SMN2DRD3HTR1AMAOBHDAC6 | |
| SCHEMBL9623994 | 0.78 | KDM4E (0.43) | SMN1; SMN2DRD2DRD5DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116986-A | HETEROAROMATIC AMINE DERIVATIVES | DR. KARL THOMAE GMBH (DE) | 1992-05-26 | — | — | US | disclosed |
| US-4912115-A | Cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1990-03-27 | — | — | US | disclosed |