Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.56 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177994 | 0.98 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2EPHX2MAPK1ALDH1A1 | |
| SCHEMBL29161807 | 0.96 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2EPHX2MAPK1ALDH1A1 | |
| SCHEMBL11695495 | 0.96 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2EPHX2MAPK1ALDH1A1 | |
| SCHEMBL11694993 | 0.96 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2EPHX2MAPK1ALDH1A1 | |
| SCHEMBL4807878 | 0.96 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2EPHX2MAPK1ALDH1A1 | |
| SCHEMBL5050870 | 0.96 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2EPHX2MAPK1ALDH1A1 | |
| SCHEMBL462110 | 0.96 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2EPHX2MAPK1ALDH1A1 | |
| SCHEMBL2785000 | 0.96 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2EPHX2MAPK1ALDH1A1 | |
| SCHEMBL27760620 | 0.96 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2EPHX2MAPK1ALDH1A1 | |
| SCHEMBL25112 | 0.94 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2EPHX2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0172448-B1 | SOLID LITHIUM AND AMMONIUM SALTS OF POLY(ACRYLAMIDOMETHYLPROPANESULFONIC ACID) AND USE THEREOF TO THICKEN HIGHLY POLAR ORGANIC SOLVENTS | HENKEL CORPORATION (a Delaware corp.) (US) | 1992-02-05 | — | — | EP | disclosed |
| EP-0172448-A2 | Solid lithium and ammonium salts of poly(acrylamidomethylpropanesulfonic acid) and use thereof to thicken highly polar organic solvents | HENKEL CORPORATION (a Delaware corp.) (US) | 1986-02-26 | — | — | EP | disclosed |