SCHEMBL462110

SCHEMBL462110

C=CC(=O)NCCCCCS(=O)(=O)O

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.61
ZDHHC2 Q9UIJ5 1/20 0.61
EPHX2 P34913 2/20 0.49
ALDH1A1 P00352 3/20 0.45
MAPK1 P28482 2/20 0.45
TSHR P16473 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
TGM2 P21980 7/20 0.44
MAPT P10636 1/20 0.39
GAA P10253 1/20 0.38
APP P05067 1/20 0.35
KDM4E B2RXH2 1/20 0.35
HIF1A Q16665 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A2 O94788 1/20 0.32
ALDH2 P05091 1/20 0.32
ALDH1A3 P47895 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4807878 1.00 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL27760620 1.00 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL29161807 1.00 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL11694993 1.00 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL5050870 1.00 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL11695495 1.00 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL177994 0.98 ZDHHC20 (0.58) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL2785000 0.96 ZDHHC20 (0.56) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL9625870 0.96 ZDHHC20 (0.56) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
Dimethylamine SCHEMBL11694933 0.95 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0966948-B1 Cosmetic composition containing an anionic polymer and an acrylic terpolymer and use of said composition for treating keratinic materials OREAL (FR) 2002-05-22 EP claimed
US-6294158-B1 HAIR GELS. L'OREAL (FR) 2001-09-25 US claimed
US-4971835-A QUATERNARY AMMONIUM COMPOUNDS OR AMINES FOR IMPREGNATION IN LEATHER Hoecsht Aktiengesellschaft (DE) 1990-11-20 US claimed
EP-3797636-B1 METHOD FOR SHAPING HAIR USING SURFACTANTS OREAL (FR) 2024-02-07 EP disclosed
EP-2651372-B2 AEROSOL DEVICE HAVING TWO COMPARTMENTS INCLUDING AN ALCOHOLIC OR HYDROALCOHOLIC HAIRSTYLING COMPOSITION, AND HAIRSTYLING METHOD OREAL (FR) 2023-10-25 EP disclosed
US-11654093-B2 Monophasic appearance cosmetic hair composition comprising a particular nonionic surfactant L'OREAL (FR) 2023-05-23 US disclosed
US-20230056796-A1 COMPOSITION COMPRISING A CATIONIC CELLULOSE-BASED POLYMER, A SULFONIC ANIONIC POLYMER AND A FIXING POLYMER L'OREAL (FR) 2023-02-23 US disclosed
US-20230031235-A1 PROCESS FOR THE COSMETIC TREATMENT OF KERATIN FIBRES USING A RARE-EARTH METAL AND A PARTICULAR POLYMER L'OREAL (FR) 2023-02-02 US disclosed
WO-2023275284-A1 COMPOSITION IN EMULSION FORM COMPRISING AN AMPHOTERIC SURFACTANT, A FATTY SUBSTANCE AND A PROPELLANT L'OREAL (FR) 2023-01-05 WO disclosed
WO-2023275283-A1 COMPOSITION OF SINGLE-PHASE APPEARANCE COMPRISING AN ANIONIC SURFACTANT AND AN AMPHOTERIC SURFACTANT L'OREAL (FR) 2023-01-05 WO disclosed
WO-2023275282-A1 COMPOSITION OF SINGLE-PHASE APPEARANCE COMPRISING A NONIONIC SURFACTANT AND AN AMPHOTERIC SURFACTANT L'OREAL (FR) 2023-01-05 WO disclosed
US-6039933-A COMPRISING A COSMETICALLY ACCEPTABLE MEDIUM CONTAINING AT LEAST ONE BINDING POLYMER, AT LEAST ONE OXYALKYLENE SILICONE AND AT LEAST 30 WT % OF A WATER-SOLUBLE SOLVENT HAVING A BOILING POINT LOWER THAN 85 DEGREES C L'OREAL (FR) 2000-03-21 US disclosed
US-5620684-A Cosmetic compositions for maintaining hairstyle possessing improved fixing power L'OREAL (FR) 1997-04-15 US disclosed
US-5080888-A COMPOSITION AND PROCESS FOR TREATING KERATINIC SUBSTANCES WITH AT LEAST ONE ANIONIC POLYMER AND AT LEAST ONE QUATERNIZED PROTEIN L'OREAL (FR) 1992-01-14 US disclosed
US-5008105-A Applying to hair L'OREAL (FR) 1991-04-16 US disclosed
US-4796646-A HAIR, SKIN OR NAILS L'OREAL (FR) 1989-01-10 US disclosed
US-4668508-A Composition for the hair, containing at least one cationic polymer, one anionic polymer, one sugar and one salt L'OREAL (FR) 1987-05-26 US disclosed
US-4664835-A SHAMPOO, LOTIONS L'OREAL (FR) 1987-05-12 US disclosed
US-4657690-A NONIONIC SURFACTANT AND ANIONIC POLYMER L'OREAL (FR) 1987-04-14 US disclosed
US-4008293-A ACRYLIC COPOLYMER, AMINOPLAST, BINDER PPG INDUSTRIES, INC. (US) 1977-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230056796-A1 COMPOSITION COMPRISING A CATIONIC CELLULOSE-BASED POLYMER, A SULFONIC ANIONIC POLYMER AND A FIXING POLYMER KRT18, PRKDC, SUCLG1 ZDHHC20 702/4885ZDHHC2 1387/4885EPHX2 4728/4885
US-11654093-B2 Monophasic appearance cosmetic hair composition comprising a particular nonionic surfactant KRT18, POLR1C, PRKDC ZDHHC20 461/4885ZDHHC2 1658/4885EPHX2 3198/4885
US-20230031235-A1 PROCESS FOR THE COSMETIC TREATMENT OF KERATIN FIBRES USING A RARE-EARTH METAL AND A PARTICULAR POLYMER KRT18, KIF5B, DSG1 ZDHHC20 813/4885ZDHHC2 1205/4885EPHX2 4339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.