SCHEMBL4807878

SCHEMBL4807878

C=CC(=O)NCCCCCCCCCCCCS(=O)(=O)O

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.61
ZDHHC2 Q9UIJ5 1/20 0.61
EPHX2 P34913 2/20 0.49
ALDH1A1 P00352 3/20 0.45
MAPK1 P28482 2/20 0.45
TSHR P16473 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
TGM2 P21980 7/20 0.44
MAPT P10636 1/20 0.39
GAA P10253 1/20 0.38
APP P05067 1/20 0.35
KDM4E B2RXH2 1/20 0.35
HIF1A Q16665 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A2 O94788 1/20 0.32
ALDH2 P05091 1/20 0.32
ALDH1A3 P47895 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27760620 1.00 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL29161807 1.00 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL11694993 1.00 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL5050870 1.00 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL462110 1.00 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL11695495 1.00 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL177994 0.98 ZDHHC20 (0.58) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL2785000 0.96 ZDHHC20 (0.56) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
SCHEMBL9625870 0.96 ZDHHC20 (0.56) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1
Dimethylamine SCHEMBL11694933 0.95 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX2ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101560004-B hydroximic acid-type polymeric flocculant for removing heavy metal ions in sewage HUNAN NORMAL UNIVERSITY (CN) 2012-02-01 CN claimed
CN-101560005-B Amphoteric polymeric flocculant for removing phosphor in sewage UNIV HUNAN NORMAL 2011-01-05 CN claimed
CN-101560005-A Amphoteric polymeric flocculant for removing phosphor in sewage UNIV HUNAN NORMAL (CN) 2009-10-21 CN claimed
CN-101560004-A hydroximic acid-type polymeric flocculant for removing heavy metal ions in sewage UNIV HUNAN NORMAL (CN) 2009-10-21 CN claimed
CN-101560004-B hydroximic acid-type polymeric flocculant for removing heavy metal ions in sewage HUNAN NORMAL UNIVERSITY (CN) 2012-02-01 CN disclosed
CN-101560005-B Amphoteric polymeric flocculant for removing phosphor in sewage UNIV HUNAN NORMAL 2011-01-05 CN disclosed
CN-101560004-A hydroximic acid-type polymeric flocculant for removing heavy metal ions in sewage UNIV HUNAN NORMAL (CN) 2009-10-21 CN disclosed
CN-101560005-A Amphoteric polymeric flocculant for removing phosphor in sewage UNIV HUNAN NORMAL (CN) 2009-10-21 CN disclosed
US-7446087-B2 Compositions comprising low-DP polymerized surfactants and methods of use thereof JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2008-11-04 US disclosed
US-7446088-B2 Compositions comprising low-DP polymerized surfactants and methods of use thereof JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2008-11-04 US disclosed
US-7417020-B2 low-irritation; for treating the skin, hair, or vaginal region JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2008-08-26 US disclosed
US-20070259797-A1 Compositions comprising low-DP polymerized surfactants and methods of use thereof JOHNSON & JOHNSON CONSUMER INC. 2007-11-08 US disclosed
US-20070259798-A1 Compositions comprising low-DP polymerized surfactants and methods of use thereof JOHNSON & JOHNSON CONSUMER INC. 2007-11-08 US disclosed
US-20070259796-A1 Compositions comprising low-DP polymerized surfactants and methods of use thereof JOHNSON & JOHNSON CONSUMER INC. 2007-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070259796-A1 Compositions comprising low-DP polymerized surfactants and methods of use thereof DSG1, DSP, CUTA ZDHHC20 670/4885ZDHHC2 1446/4885EPHX2 351/4885
US-20070259797-A1 Compositions comprising low-DP polymerized surfactants and methods of use thereof DSG1, DSP, CUTA ZDHHC20 670/4885ZDHHC2 1446/4885EPHX2 351/4885
US-20070259798-A1 Compositions comprising low-DP polymerized surfactants and methods of use thereof DSG1, DSP, CUTA ZDHHC20 670/4885ZDHHC2 1446/4885EPHX2 351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.