Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.37 |
| ▸ | RARG | P13631 | 6/20 | 0.37 |
| ▸ | RARA | P10276 | 5/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 7/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455621 | 0.77 | PGR (0.40) | RARBRARGRARACYP2A6ALDH1A1 | |
| SCHEMBL3838099 | 0.77 | RARB (0.57) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL9860639 | 0.76 | CMA1 (0.40) | ALDH1A1HSD17B10KDM4ETP53SMN1; SMN2 | |
| SCHEMBL9626255 | 0.73 | RXRA (0.37) | RARBRARGRARACYP2A6RXRA | |
| SCHEMBL10452858 | 0.72 | PDK2 (0.41) | ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL9626471 | 0.72 | RARB (0.43) | RARBRARGRARACYP2A6RXRA | |
| SCHEMBL10667658 | 0.71 | RARB (0.71) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL10667654 | 0.71 | RARB (0.71) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL4711216 | 0.71 | PRKDC (0.38) | RXRAALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL13716890 | 0.70 | PGR (0.40) | RARBRARGRARACYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339521-B1 | PROCESS FOR MANUFACTURING TETRALIN DERIVATIVES, AND TETRALIN DERIVATIVES | BASF Aktiengesellschaft (DE) | 1992-03-18 | — | — | EP | claimed |
| EP-0339521-A1 | Process for manufacturing tetralin derivatives, and tetralin derivatives | BASF Aktiengesellschaft (DE) | 1989-11-02 | — | — | EP | claimed |
| EP-0339521-B1 | PROCESS FOR MANUFACTURING TETRALIN DERIVATIVES, AND TETRALIN DERIVATIVES | BASF Aktiengesellschaft (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4950369-A | Preparation of tetralin derivatives, and novel tetralin derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1990-08-21 | — | — | US | disclosed |
| EP-0339521-A1 | Process for manufacturing tetralin derivatives, and tetralin derivatives | BASF Aktiengesellschaft (DE) | 1989-11-02 | — | — | EP | disclosed |