Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722212 | 0.90 | HTR1A (0.52) | MAPTTP53HTR1AADRA1AADRA2C | |
| SCHEMBL22221259 | 0.84 | MAPT (0.55) | MAPTTP53SLC1A5HTR1AADRA1A | |
| SCHEMBL7805002 | 0.83 | HTR1A (0.61) | MAPTTP53HTR1AADRA1AADRA2C | |
| SCHEMBL29799217 | 0.83 | ALDH1A1 (0.48) | MAPTTP53HTR1AADRA1AADRA2C | |
| SCHEMBL20257761 | 0.82 | SLC1A5 (0.55) | MAPTSLC1A5HTR1AADRA1AADRA1D | |
| SCHEMBL9625666 | 0.81 | HTR1A (0.56) | MAPTTP53HTR1AADRA1AADRA2C | |
| SCHEMBL23004958 | 0.81 | SLC1A5 (0.54) | MAPTSLC1A5HTR1AADRA1AADRA1D | |
| SCHEMBL5644007 | 0.81 | SLC1A5 (0.54) | MAPTSLC1A5HTR1AADRA1AADRA1D | |
| SCHEMBL21726729 | 0.80 | MAPT (0.52) | MAPTTP53SLC1A5HTR1AADRA1A | |
| SCHEMBL21844358 | 0.79 | GAA (0.60) | MAPTSLC1A5HTR1AADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469684-A1 | Polyimide compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-02-05 | — | — | EP | disclosed |