Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625666 | 0.95 | HTR1A (0.56) | HTR1ADRD2ADRA2CADRA2AADRA2B | |
| SCHEMBL9722212 | 0.90 | HTR1A (0.52) | HTR1ADRD2ADRA2CADRA2AADRA2B | |
| SCHEMBL21473685 | 0.90 | HTR1A (0.52) | HTR1ADRD2ADRA2CADRA2AADRA2B | |
| SCHEMBL22700917 | 0.87 | HTR1A (0.50) | HTR1ADRD2ADRA2CADRA2AADRA2B | |
| SCHEMBL22221259 | 0.87 | MAPT (0.55) | HTR1ADRD2ADRA2CADRA2AADRA2B | |
| SCHEMBL30705310 | 0.85 | GABRA1 (0.51) | HTR1ADRD2ADRA2CADRA2AADRA2B | |
| SCHEMBL12635300 | 0.85 | GABRA1 (0.51) | HTR1ADRD2ADRA2CADRA2AADRA2B | |
| SCHEMBL18169335 | 0.84 | L3MBTL1 (0.48) | HTR1ADRD2ADRA2CADRA2AADRA2B | |
| SCHEMBL21726729 | 0.83 | MAPT (0.52) | HTR1ADRD2ADRA2CADRA2AADRA2B | |
| SCHEMBL9625890 | 0.83 | MAPT (0.55) | HTR1ADRD2ADRA2CADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866377-B | Ether bond breaking method of phenyl alkyl ether | 荆楚理工学院 | 2020-06-09 | — | — | CN | disclosed |
| US-10385063-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-08-20 | — | — | US | disclosed |
| CN-105979942-B | For treatment or lenitive sulfamate derivatives | 比皮艾思药物研发有限公司 | 2018-12-07 | — | — | CN | disclosed |
| US-10081615-B2 | Sulfamate derivative compounds for use in treating or alleviating pain | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2018-09-25 | — | — | US | disclosed |
| US-20180111948-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
| US-9944608-B2 | Herbicidal pyridazinone derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-17 | — | — | US | disclosed |
| US-9944608-B2 | Herbicidal pyridazinone derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-17 | — | — | US | disclosed |
| EP-3079687-B1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO-PHARM SOLUTIONS CO LTD (KR) | 2018-02-28 | — | — | EP | disclosed |
| EP-3079687-B1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO-PHARM SOLUTIONS CO LTD (KR) | 2018-02-28 | — | — | EP | disclosed |
| US-20170347654-A1 | Herbicidal Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-07 | — | — | US | disclosed |
| US-20010031766-A1 | Prostaglandin receptor ligands | MERCK FROSST CANADA & CO. | 2001-10-18 | — | — | US | disclosed |
| EP-1119542-A1 | PROSTAGLANDIN RECEPTOR LIGANDS | Merck Frosst Canada & Co. (CA) | 2001-08-01 | — | — | EP | disclosed |
| US-6211197-B1 | CARBOXYLIC ACID OR TETRAZOLE DERIVATES; ANALGESICS, ANTIPYRETICS, AND ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | MERCK FROSST CANADA & CO. (CA) | 2001-04-03 | — | — | US | disclosed |
| WO-2000020371-A1 | PROSTAGLANDIN RECEPTOR LIGANDS | MERCK FROSST CANADA & CO. (CA) | 2000-04-13 | — | — | WO | disclosed |
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |
| EP-0733033-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |
| US-5541286-A | Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids | SCIOS NOVA INC. (US) | 1996-07-30 | — | — | US | disclosed |
| WO-1996011902-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-04-25 | — | — | WO | disclosed |
| US-5444048-A | Antiinflammatory agents, analgesics | SCIOS NOVA, INC. (US) | 1995-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170347654-A1 | Herbicidal Compounds | DDT, GLRX3, AGXT | HTR1A 3398/4885DRD2 808/4885ADRA2C 2460/4885 |
| US-10385063-B2 | Herbicidal compounds | DDT, DAO, HPD | HTR1A 3973/4885DRD2 461/4885ADRA2C 2689/4885 |
| US-20010031766-A1 | Prostaglandin receptor ligands | PTGER1, PTGER2, PTGFR | HTR1A 230/4885DRD2 799/4885ADRA2C 123/4885 |
| US-20180111948-A1 | HERBICIDAL COMPOUNDS | DDT, DAO, HPD | HTR1A 3927/4885DRD2 449/4885ADRA2C 2647/4885 |
| US-10081615-B2 | Sulfamate derivative compounds for use in treating or alleviating pain | SULT2A1, SULT1A1, TRPV1 | HTR1A 761/4885DRD2 395/4885ADRA2C 2472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.