SCHEMBL9625893

SCHEMBL9625893

C=CCc1ccccc1Oc1c(C)cccc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
ADRA2C P18825 5/20 0.42
HTR1A P08908 4/20 0.42
ADRB2 P07550 3/20 0.42
ADRB1 P08588 3/20 0.42
LMNA P02545 2/20 0.42
KCNH2 Q12809 2/20 0.42
ADRB3 P13945 1/20 0.42
SLC6A2 P23975 1/20 0.42
BDKRB2 P30411 1/20 0.42
SLC6A4 P31645 1/20 0.42
ADRA1A P35348 1/20 0.42
HTR2B P41595 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
KDM4E B2RXH2 2/20 0.41
PMP22 Q01453 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10592641 0.84 ALDH1A1 (0.40) ALDH1A1ADRA2CHTR1AADRB2ADRB1
SCHEMBL10790494 0.82 GABRA1 (0.44) ALDH1A1ADRA2CLMNAKCNH2SLC6A4
SCHEMBL88415 0.82 ALDH1A1 (0.50) ALDH1A1ADRA2CHTR1AADRB2ADRB1
SCHEMBL3744643 0.80 ALDH1A1 (0.49) ALDH1A1ADRA2CHTR1AADRB2ADRB1
SCHEMBL3730543 0.80 ALDH1A1 (0.49) ALDH1A1ADRA2CHTR1AADRB2ADRB1
Water SCHEMBL8939878 0.80 ALDH1A1 (0.49) ALDH1A1ADRA2CHTR1AADRB2ADRB1
Ethylene SCHEMBL173231 0.80 ALDH1A1 (0.49) ALDH1A1ADRA2CHTR1AADRB2ADRB1
SCHEMBL11122579 0.78 ALDH1A1 (0.40) ALDH1A1TSHRKDM4E
Formaldehyde SCHEMBL4291615 0.78 ICAM1 (0.48) ALDH1A1ADRA2CHTR1AADRB2ADRB1
SCHEMBL28307193 0.77 GABRA1 (0.43) ALDH1A1ADRA2CLMNAKCNH2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0469684-A1 Polyimide compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-02-05 EP disclosed