Water

Water

SCHEMBL8939878

C=CCc1ccccc1Oc1ccccc1CC=C.O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2C known ✓ P18825 4/20 0.46
HTR1A known ✓ P08908 3/20 0.46
ADRA2A known ✓ P08913 3/20 0.46
ADRA2B known ✓ P18089 3/20 0.46
ADRB2 known ✓ P07550 3/20 0.45
ADRB1 known ✓ P08588 3/20 0.45
ADRB3 known ✓ P13945 1/20 0.45
SLC6A2 known ✓ P23975 1/20 0.45
SLC6A4 known ✓ P31645 1/20 0.45
ADRA1A known ✓ P35348 1/20 0.45
HTR2B known ✓ P41595 1/20 0.45
ALDH1A1 P00352 3/20 0.49
KDM4E B2RXH2 3/20 0.49
NISCH Q9Y2I1 1/20 0.46
ICAM1 P05362 1/20 0.46
SELE P16581 1/20 0.46
VCAM1 P19320 1/20 0.46
LMNA P02545 2/20 0.45
BDKRB2 P30411 1/20 0.45
KCNH2 Q12809 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88415 0.98 ALDH1A1 (0.50) ALDH1A1KDM4EADRA2CHTR1AADRA2A
SCHEMBL3744643 0.96 ALDH1A1 (0.49) ALDH1A1KDM4EADRA2CHTR1AADRA2A
Ethylene SCHEMBL173231 0.96 ALDH1A1 (0.49) ALDH1A1KDM4EADRA2CHTR1AADRA2A
SCHEMBL3730543 0.96 ALDH1A1 (0.49) ALDH1A1KDM4EADRA2CHTR1AADRA2A
Formaldehyde SCHEMBL4291615 0.94 ICAM1 (0.48) ALDH1A1KDM4EADRA2CHTR1AADRA2A
Ethylene Glycol SCHEMBL366742 0.90 ALDH1A1 (0.48) ALDH1A1KDM4EADRA2CHTR1AADRA2A
Oxirane SCHEMBL27501323 0.88 ADRB2 (0.50) ALDH1A1KDM4EADRA2CHTR1AADRA2A
SCHEMBL9352980 0.88 HRH1 (0.47) ALDH1A1KDM4EADRA2CHTR1AADRA2A
Sulfuric Acid SCHEMBL1678480 0.87 ICAM1 (0.47) ALDH1A1KDM4EADRA2CHTR1AADRA2A
Phosphoric Acid SCHEMBL4078188 0.87 ICAM1 (0.47) ALDH1A1KDM4EADRA2CHTR1AICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8176392-A None JP disclosed
US-12013644-B2 Method for manufacturing electronic device FUJIFILM CORPORATION (JP) 2024-06-18 US disclosed
US-11898081-B2 Ruthenium-etching solution, method for manufacturing ruthenium-etching solution, method for processing object to be processed, and method for manufacturing ruthenium-containing wiring TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-13 US disclosed
US-11873443-B2 Composition and production method of same, and dispersing agent NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2024-01-16 US disclosed
US-11807792-B2 Semiconductor processing liquid and method for processing substrate TOKYO OHKA KOGYO CO., LTD. (JP) 2023-11-07 US disclosed
US-11773324-B2 Semiconductor processing liquid and method for processing substrate TOKYO OHKA KOGYO CO., LTD. (JP) 2023-10-03 US disclosed
US-11686002-B2 Method for manufacturing ruthenium wiring TOKYO OHKA KOGYO CO., LTD. (JP) 2023-06-27 US disclosed
WO-2023282287-A1 CLEANING AGENT COMPOSITION FOR POST-CMP STEP 株式会社日本触媒 2023-01-12 WO disclosed
US-11518937-B2 Etching solution and method for manufacturing semiconductor element TOKYO OHKA KOGYO CO., LTD. (JP) 2022-12-06 US disclosed
US-20220372369-A1 SEMICONDUCTOR PROCESSING LIQUID AND METHOD FOR PROCESSING SUBSTRATE TOKYO OHKA KOGYO CO LTD (JP) 2022-11-24 US disclosed
WO-2020255602-A1 POLISHING SOLUTION AND CHEMICAL-MECHANICAL POLISHING METHOD 富士フイルム株式会社 2020-12-24 WO disclosed
WO-2020255581-A1 POLISHING FLUID AND CHEMICAL MECHANICAL POLISHING METHOD 富士フイルム株式会社 2020-12-24 WO disclosed
US-20200255465-A1 LIGNIN DERIVATIVE COMPOUND AND USE THEREOF NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2020-08-13 US disclosed
US-20200211856-A1 ETCHING SOLUTION, AND METHOD OF PRODUCING SEMICONDUCTOR ELEMENT TOKYO OHKA KOGYO CO., LTD. (JP) 2020-07-02 US disclosed
EP-3674352-A1 LIGNIN DERIVATIVE COMPOUND AND USE THEREOF Nippon Paper Industries Co., Ltd. (JP) 2020-07-01 EP disclosed
US-20200190672-A1 ETCHING SOLUTION, METHOD FOR PROCESSING OBJECT TO BE PROCESSED, AND METHOD FOR MANUFACTURING SEMICONDUCTOR ELEMENT TOKYO OHKA KOGYO CO., LTD. (JP) 2020-06-18 US disclosed
CN-107022421-B Cleaning method and method for manufacturing semiconductor device 富士胶片株式会社 2020-04-28 CN disclosed
CN-110997759-A Lignin derivative compounds and uses thereof 日本制纸株式会社 2020-04-10 CN disclosed
US-20190025702-A1 TREATMENT LIQUID FOR MANUFACTURING SEMICONDUCTOR AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2019-01-24 US disclosed
JP-H08176392-A MODIFIED PROPYLENE POLYMER COMPOSITION AND SHEET AND MOLDING MATERIAL PRODUCED BY USING THE COMPOSITION DAINIPPON INK & CHEM INC 1996-07-09 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200255465-A1 LIGNIN DERIVATIVE COMPOUND AND USE THEREOF LSS, SELL, DDT ADRA2C 3843/4885HTR1A 4690/4885ADRA2A 3953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.